Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1711015 | 0.85 | MAPT (0.53) | GAASMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL1120384 | 0.85 | GAA (0.49) | GAASMN1; SMN2ALDH1A1RAB9ACNR1 | |
| Hydrochloric Acid SCHEMBL119951 | 0.84 | GAA (0.48) | GAASMN1; SMN2ALDH1A1RAB9ACNR1 | |
| SCHEMBL990693 | 0.79 | GAA (0.47) | GAASMN1; SMN2RAB9ACNR1LMNA | |
| SCHEMBL5045220 | 0.74 | TAAR1 (0.57) | GAASMN1; SMN2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL991931 | 0.73 | TAAR1 (0.52) | GAASMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL7488316 | 0.73 | RAB9A (0.49) | SMN1; SMN2ALDH1A1RAB9AL3MBTL1MAPT | |
| SCHEMBL25804595 | 0.72 | GAA (0.49) | GAASMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL13232446 | 0.70 | PLK1 (0.47) | GAASMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL989796 | 0.70 | TAAR1 (0.55) | SMN1; SMN2RAB9ACNR1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011008312-A2 | INDOLE AND INDOLINE DERIVATIVES AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2011-01-20 | — | — | WO | disclosed |