SCHEMBL9920864

SCHEMBL9920864

c1cc2ccc3ccc(-c4cccc5c4sc4ccccc45)c4ccc(c1)c2c34

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 1/20 0.46
ALOX5 P09917 1/20 0.46
CYP1A2 P05177 3/20 0.42
ERBB2 P04626 1/20 0.42
FYN P06241 1/20 0.42
MAOA P21397 1/20 0.42
ACHE P22303 1/20 0.42
AHR P35869 1/20 0.42
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 4/20 0.41
HPGD P15428 3/20 0.41
THRB P10828 1/20 0.41
PRKDC P78527 7/20 0.41
GPR3 P46089 1/20 0.39
PIK3CD O00329 2/20 0.39
PIK3CB P42338 2/20 0.39
TSHR P16473 3/20 0.37
CYP3A4 P08684 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
BRD4 O60885 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14101613 0.97 PARP14 (0.48) PARP14ALOX5CYP1A2ERBB2FYN
SCHEMBL16307760 0.93 ALOX5 (0.46) PARP14ALOX5CYP1A2ERBB2FYN
SCHEMBL9921015 0.91 ALOX5 (0.47) PARP14ALOX5CYP1A2ERBB2FYN
SCHEMBL9920995 0.90 ALOX5 (0.50) PARP14ALOX5CYP1A2ERBB2FYN
SCHEMBL14101614 0.90 ALOX5 (0.47) PARP14ALOX5CYP1A2ERBB2FYN
SCHEMBL14101615 0.90 ALOX5 (0.46) PARP14ALOX5CYP1A2ALDH1A1HSD17B10
SCHEMBL125912 0.90 ALOX5 (0.43) PARP14ALOX5CYP1A2ERBB2FYN
SCHEMBL14101657 0.90 ALOX5 (0.52) PARP14ALOX5CYP1A2ERBB2FYN
SCHEMBL13658622 0.88 L3MBTL1 (0.47) PARP14ALOX5MAOAALDH1A1HSD17B10
SCHEMBL13682489 0.88 ALOX5 (0.49) PARP14ALOX5CYP1A2ERBB2FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11139438-B2 Organic electroluminescent element KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2021-10-05 US disclosed
US-11063220-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-07-13 US disclosed
US-20190280209-A1 ORGANIC ELECTROLUMINESCENT ELEMENT JNC CORPORATION (JP) 2019-09-12 US disclosed
US-20190229277-A1 ORGANIC ELECTROLUMINESCENT ELEMENT KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2019-07-25 US disclosed
EP-2463352-B1 Light emitting device material and light emitting device TORAY INDUSTRIES (JP) 2018-05-02 EP disclosed
EP-1942171-B1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES (JP) 2018-04-18 EP disclosed
US-20140367654-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-18 US disclosed
US-20140367654-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-18 US disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
EP-2463351-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
EP-2463352-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
US-20080166594-A1 BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-07-10 US disclosed
US-20080166594-A1 BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-07-10 US disclosed
EP-1942171-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2008-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190229277-A1 ORGANIC ELECTROLUMINESCENT ELEMENT ELP1, NFE2L2, ESR2 PARP14 3055/4885ALOX5 486/4885CYP1A2 293/4885
US-20090096356-A1 Light-emitting device material and light-emitting device PRMT9, CCNL2, MRPL9 PARP14 2553/4885ALOX5 1517/4885CYP1A2 249/4885
US-11139438-B2 Organic electroluminescent element ELP1, NFE2L2, ESR2 PARP14 3055/4885ALOX5 486/4885CYP1A2 293/4885
US-20080166594-A1 BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME CYBA, BPNT1, TYR PARP14 1219/4885ALOX5 1860/4885CYP1A2 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.