SCHEMBL9920967

SCHEMBL9920967

Cc1ccc(-c2ccc3ccc4c(-c5cc(-c6cc(-c7ccccc7)cc(-c7ccccc7)c6)cc(-n6c7ccccc7c7ccccc76)c5)ccc5ccc2c3c54)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C4 P17516 1/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 2/20 0.36
ATM Q13315 1/20 0.36
HPRT1 P00492 1/20 0.36
ALDH1A1 P00352 4/20 0.35
RXFP1 Q9HBX9 2/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
LMNA P02545 2/20 0.33
COMT P21964 1/20 0.33
NPC1 O15118 1/20 0.33
NTSR1 P30989 1/20 0.33
RAB9A P51151 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9920740 1.00 AKR1C4 (0.37) AKR1C4AKR1C3AKR1C2AKR1C1L3MBTL1
SCHEMBL9920783 0.95 AKR1C4 (0.39) AKR1C4AKR1C3AKR1C2AKR1C1L3MBTL1
SCHEMBL9921089 0.93 KDM4E (0.37) AKR1C4AKR1C3AKR1C2AKR1C1L3MBTL1
SCHEMBL9920636 0.92 TSPO (0.35) AKR1C4AKR1C3AKR1C2AKR1C1L3MBTL1
SCHEMBL9920642 0.92 HPRT1 (0.35) AKR1C4AKR1C3AKR1C2AKR1C1KDM4E
SCHEMBL9920762 0.91 ALDH1A1 (0.39) AKR1C4AKR1C3AKR1C2AKR1C1KDM4E
SCHEMBL9920950 0.91 ALDH1A1 (0.35) AKR1C4AKR1C3AKR1C2AKR1C1L3MBTL1
SCHEMBL9920970 0.91 L3MBTL1 (0.33) AKR1C4AKR1C3AKR1C2AKR1C1L3MBTL1
SCHEMBL9920973 0.90 L3MBTL1 (0.35) AKR1C4AKR1C3AKR1C2AKR1C1L3MBTL1
SCHEMBL9920984 0.90 ALDH1A1 (0.36) AKR1C4AKR1C3AKR1C2AKR1C1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463352-B1 Light emitting device material and light emitting device TORAY INDUSTRIES (JP) 2018-05-02 EP disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
EP-2463352-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
EP-2463351-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
EP-1942171-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2008-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090096356-A1 Light-emitting device material and light-emitting device PRMT9, CCNL2, MRPL9 AKR1C4 3141/4885AKR1C3 2786/4885AKR1C2 3521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.