Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15934293 | 0.81 | MTNR1A (0.46) | ALDH1A1L3MBTL1MTNR1AHTTALOX15 | |
| SCHEMBL21661030 | 0.81 | MTNR1A (0.46) | ALDH1A1L3MBTL1MTNR1AHTTALOX15 | |
| SCHEMBL8050286 | 0.81 | MTNR1A (0.46) | ALDH1A1L3MBTL1MTNR1AHTTALOX15 | |
| SCHEMBL13472620 | 0.80 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL20905584 | 0.77 | MTNR1A (0.45) | ALDH1A1L3MBTL1MTNR1A | |
| SCHEMBL18378505 | 0.72 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1HTT | |
| SCHEMBL26631609 | 0.72 | — | — | |
| SCHEMBL12808809 | 0.71 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL24667752 | 0.69 | — | — | |
| SCHEMBL805496 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010185-B1 | DIHYDROTHIENOPYRIMIDINE FOR TREATING INFLAMMATORY DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2012-06-13 | — | — | EP | disclosed |