Sugi Predict

Sugi Predict / Compounds / SCHEMBL992215

SCHEMBL992215

SCHEMBL992215

CC(C)(C(=O)O)c1ccc(CCO)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PPARA Q07869 3/20 0.57
▸ HRH3 Q9Y5N1 1/20 0.48
▸ CYP4F2 P78329 3/20 0.46
▸ CYP4A11 Q02928 3/20 0.46
▸ SLC13A5 Q86YT5 2/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ CA2 P00918 2/20 0.43
▸ ESRRG P62508 1/20 0.41
▸ APP P05067 1/20 0.41
▸ CA12 O43570 1/20 0.40
▸ CA1 P00915 1/20 0.40
▸ CA4 P22748 1/20 0.40
▸ CA6 P23280 1/20 0.40
▸ CA5A P35218 1/20 0.40
▸ CA7 P43166 1/20 0.40
▸ CA9 Q16790 1/20 0.40
▸ CA14 Q9ULX7 1/20 0.40
▸ CA5B Q9Y2D0 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ PPARG P37231 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28340064 0.98 PPARA (0.56) PPARAHRH3CYP4F2CYP4A11SLC13A5
SCHEMBL2964885 0.87 PPARA (0.54) PPARAHRH3CYP4F2CYP4A11SLC13A5
SCHEMBL11439832 0.86 HRH3 (0.49) PPARAHRH3SLC13A5ESRRG
SCHEMBL55105 0.84 PPARA (0.55) PPARAHRH3SLC13A5APPTSHR
SCHEMBL31058284 0.84 RORC (0.47) PPARAHRH3CYP4F2CYP4A11TDP1
SCHEMBL993574 0.83 HRH3 (0.47) PPARAHRH3SLC13A5ESRRGRXRA
SCHEMBL8587467 0.81 ALDH1A1 (0.58) HRH3TDP1TSHR
Hydrochloric Acid SCHEMBL11112027 0.81 TAAR1 (0.48) HRH3SLC13A5TDP1ESRRG
SCHEMBL28337701 0.81 PPARA (0.46) PPARACYP4F2CYP4A11SLC13A5TDP1
SCHEMBL3497043 0.81 MAPT (0.52) HRH3APPTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112110811-B Preparation method of bilastine intermediate 北京万全德众医药生物技术有限公司 2024-08-13 — — CN claimed
CN-112110811-A Preparation method of bilastine intermediate 北京万全德众医药生物技术有限公司 2020-12-22 — — CN claimed
CN-106146459-B Preparation method of bilastine 山东罗欣药业集团恒欣药业有限公司 2019-12-20 — — CN claimed
CN-206635252-U A kind of production system of 2 (4 (2 hydroxyethyl) phenyl) 2 methylpropanoic acids 杭州励德生物科技有限公司 2017-11-14 — — CN claimed
CN-114591292-B Bilastine intermediate compounds 鲁南制药集团股份有限公司 2025-06-17 — — CN disclosed
CN-114591291-B Bilastine intermediate compound and preparation method thereof 鲁南制药集团股份有限公司 2025-06-17 — — CN disclosed
CN-112110811-B Preparation method of bilastine intermediate 北京万全德众医药生物技术有限公司 2024-08-13 — — CN disclosed
CN-112110811-B Preparation method of bilastine intermediate 北京万全德众医药生物技术有限公司 2024-08-13 — — CN disclosed
CN-115745954-A Preparation method of bilastine intermediate 山东新时代药业有限公司 2023-03-07 — — CN disclosed
CN-112778152-B Synthesis method of bilastine intermediate 湖北英纳氏生物科技有限公司 2022-11-01 — — CN disclosed
CN-114591291-A Bilastine intermediate compound and preparation method thereof 鲁南制药集团股份有限公司 2022-06-07 — — CN disclosed
CN-113292534-B Preparation method of bilastine key intermediate 常州大学 2022-04-26 — — CN disclosed
US-8633223-B2 Process for preparation of 2-methyl-2′-phenylpropionic acid derivatives and novel intermediate compounds YUHAN CORPORATION (KR) 2014-01-21 — — US disclosed
US-8487106-B2 Process for preparation of 2-methyl-2′-phenylpropionic acid derivatives and novel intermediate compounds YUHAN CORPORATION (KR) 2013-07-16 — — US disclosed
US-20130116439-A1 PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS YUHAN CORPORATION (KR) 2013-05-09 — — US disclosed
US-20130116466-A1 PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS YUHAN CORPORATION (KR) 2013-05-09 — — US disclosed
US-8367704-B2 Process for preparation of 2-methyl-2′ phenylpropionic acid derivatives and novel intermediate compounds YUHAN CORPORATION (KR) 2013-02-05 — — US disclosed
US-20110009636-A1 PROCESS FOR THE PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS YUHAN CORPORATION (KP) 2011-01-13 — — US disclosed
EP-2240464-A2 PROCESS FOR PREPARATION OF 2-METHYL-2´-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS Yuhan Corporation (KR) 2010-10-20 — — EP disclosed
WO-2009102155-A2 PROCESS FOR PREPARATION OF 2-METHYL-2´-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS YUHAN CORPORATION (KR) 2009-08-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009636-A1 PROCESS FOR THE PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS HRH4, HCAR2, HRH1 PPARA 1576/4885HRH3 7/4885CYP4F2 327/4885
US-20130116439-A1 PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS HRH2, HRH4, HNMT PPARA 1739/4885HRH3 5/4885CYP4F2 750/4885
US-20130116466-A1 PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS HRH1, HRH2, HRH4 PPARA 1558/4885HRH3 6/4885CYP4F2 280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.