Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 3/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9918979 | 0.81 | METAP1 (0.50) | CASP3APPSRD5A1KMT2AALDH1A1 | |
| SCHEMBL12706597 | 0.79 | RAB9A (0.44) | TDP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL9918982 | 0.79 | SRD5A1 (0.50) | TDP2SRD5A1KMT2AMEN1CASP6 | |
| SCHEMBL19657308 | 0.79 | CASP3 (0.43) | TDP2CASP3SRD5A1KMT2AALDH1A1 | |
| SCHEMBL16506973 | 0.79 | TRIM24 (0.49) | CASP3KMT2AALDH1A1MEN1GAA | |
| SCHEMBL9922246 | 0.77 | ALDH1A1 (0.60) | APPKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL9922257 | 0.77 | METAP1 (0.55) | CASP3APPKMT2AALDH1A1MEN1 | |
| SCHEMBL9922248 | 0.77 | APP (0.41) | TDP2APPKMT2AALDH1A1MEN1 | |
| SCHEMBL9918985 | 0.76 | ALDH1A1 (0.64) | APPKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL17322371 | 0.76 | MAPT (0.62) | TDP2KMT2AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | TBXA2R, GP6, P2RY6 | TDP2 2409/4885CASP3 2695/4885APP 3844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.