Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL992370 | 0.84 | CASP1 (0.53) | CASP1ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL991807 | 0.84 | CASP1 (0.53) | CASP1EPHX2ERN1ALDH1A1MEN1 | |
| SCHEMBL13978206 | 0.83 | TPSAB1 (0.55) | CASP1ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL993781 | 0.83 | CASP1 (0.52) | CASP1ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL13977813 | 0.83 | CASP1 (0.52) | CASP1ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL13533564 | 0.83 | CASP1 (0.52) | CASP1EPHX2ERN1ALDH1A1MEN1 | |
| SCHEMBL13978142 | 0.83 | MAPT (0.53) | CASP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7624194 | 0.83 | CASP1 (0.68) | CASP1ALDH1A1MAPTCYP3A4PLAU | |
| SCHEMBL8870036 | 0.82 | CSNK2A2 (0.54) | CASP1EPHX2NR1H4ALDH1A1MEN1 | |
| SCHEMBL3419896 | 0.81 | CASP1 (0.50) | CASP1ERN1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451776-B1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING INC (US) | 2019-09-18 | — | — | EP | disclosed |
| US-9732047-B2 | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| EP-2240206-B1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING INC (US) | 2017-03-22 | — | — | EP | disclosed |
| EP-2240206-B1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING INC (US) | 2017-03-22 | — | — | EP | disclosed |
| US-20170029386-A9 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-02-02 | — | — | US | disclosed |
| US-9393329-B2 | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-20160185737-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2016-06-30 | — | — | US | disclosed |
| US-9266846-B2 | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2016-02-23 | — | — | US | disclosed |
| US-20150094465-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2015-04-02 | — | — | US | disclosed |
| US-20150078997-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2015-03-19 | — | — | US | disclosed |
| US-20130315822-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-11-28 | — | — | US | disclosed |
| US-8361438-B2 | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-8361438-B2 | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20120328514-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| EP-2451776-A2 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011005322-A2 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2011-01-13 | — | — | WO | disclosed |
| EP-2240206-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| US-20090252676-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC (US) | 2009-10-08 | — | — | US | disclosed |
| US-20090252676-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC (US) | 2009-10-08 | — | — | US | disclosed |
| WO-2009089022-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150094465-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | TNNT2, UACA, ELANE | CASP1 427/4885EPHX2 597/4885NR1H4 3418/4885 |
| US-20170029386-A9 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | TNNT2, UACA, ELANE | CASP1 427/4885EPHX2 597/4885NR1H4 3418/4885 |
| US-20130315822-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | TNNT2, UACA, ELANE | CASP1 427/4885EPHX2 597/4885NR1H4 3418/4885 |
| US-20160185737-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | TNNT2, UACA, ELANE | CASP1 427/4885EPHX2 597/4885NR1H4 3418/4885 |
| US-20120328514-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | TNNT2, UACA, ELANE | CASP1 427/4885EPHX2 597/4885NR1H4 3418/4885 |
| US-20150078997-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | TNNT2, UACA, ELANE | CASP1 427/4885EPHX2 597/4885NR1H4 3418/4885 |
| US-20090252676-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | TNNT2, UACA, ELANE | CASP1 427/4885EPHX2 597/4885NR1H4 3418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.