Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.39 |
| ▸ | CA7 | P43166 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15306011 | 0.79 | MAOB (0.38) | THRBCA2CA1CA12CA14 | |
| SCHEMBL24263526 | 0.78 | LMNA (0.41) | CA2CA1CA12CA14CA7 | |
| SCHEMBL6706818 | 0.77 | KMT2A (0.47) | CA2CA1CA12CA14CA7 | |
| SCHEMBL9393740 | 0.70 | ALDH1A1 (0.47) | THRBCA2CA1CA12CA14 | |
| SCHEMBL7756202 | 0.70 | ALDH1A1 (0.47) | THRBCA2CA1CA12CA14 | |
| SCHEMBL2171728 | 0.68 | KDM1A (0.47) | HSD17B10 | |
| SCHEMBL2171729 | 0.68 | KDM1A (0.47) | HSD17B10 | |
| SCHEMBL3588721 | 0.68 | KDM1A (0.47) | HSD17B10 | |
| SCHEMBL26708853 | 0.67 | ESR1 (0.54) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL17963823 | 0.65 | TRPA1 (0.39) | ALDH1A1ATMMAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076877-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |