Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | IDH2 | P48735 | 3/20 | 0.47 |
| ▸ | UBE2M | P61081 | 3/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17206706 | 0.93 | DCUN1D1 (0.52) | EPHX2LMNAIDH2UBE2MDCUN1D1 | |
| SCHEMBL9924226 | 0.93 | EPHX2 (0.53) | EPHX2LMNAIDH2UBE2MDCUN1D1 | |
| SCHEMBL9924262 | 0.91 | UBE2M (0.46) | EPHX2LMNAIDH2UBE2MDCUN1D1 | |
| SCHEMBL17206619 | 0.90 | EPHX2 (0.48) | EPHX2LMNAIDH2UBE2MDCUN1D1 | |
| SCHEMBL9924130 | 0.88 | DCUN1D1 (0.52) | EPHX2LMNAIDH2UBE2MDCUN1D1 | |
| SCHEMBL17206726 | 0.86 | EPHX2 (0.47) | EPHX2LMNAIDH2UBE2MDCUN1D1 | |
| SCHEMBL17206709 | 0.84 | TRPV1 (0.42) | EPHX2MEN1KMT2AMAOB | |
| SCHEMBL9924261 | 0.82 | TRPV1 (0.42) | EPHX2MEN1KMT2A | |
| SCHEMBL9924133 | 0.81 | EPHX2 (0.47) | EPHX2LMNAIDH2UBE2MDCUN1D1 | |
| SCHEMBL17206719 | 0.80 | DCUN1D1 (0.47) | EPHX2LMNAIDH2UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |