Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 2/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924227 | 0.91 | EPHX2 (0.52) | UBE2MDCUN1D1MEN1KMT2AEPHX2 | |
| SCHEMBL17206706 | 0.90 | DCUN1D1 (0.52) | UBE2MDCUN1D1MEN1KMT2AEPHX2 | |
| SCHEMBL9924214 | 0.90 | MEN1 (0.49) | MEN1KMT2AEPHX2NPC1LMNA | |
| SCHEMBL9924130 | 0.89 | DCUN1D1 (0.52) | UBE2MDCUN1D1MEN1KMT2AEPHX2 | |
| SCHEMBL9924261 | 0.87 | TRPV1 (0.42) | MEN1KMT2AEPHX2TRPV1MRGPRX4 | |
| SCHEMBL9924131 | 0.87 | NPC1 (0.50) | MEN1KMT2AEPHX2NPC1LMNA | |
| SCHEMBL17206718 | 0.86 | UBE2M (0.43) | UBE2MDCUN1D1MEN1KMT2AEPHX2 | |
| SCHEMBL9924260 | 0.86 | MEN1 (0.46) | MEN1KMT2AEPHX2NPC1LMNA | |
| SCHEMBL17206709 | 0.85 | TRPV1 (0.42) | MEN1KMT2AEPHX2TRPV1MRGPRX4 | |
| SCHEMBL9924226 | 0.84 | EPHX2 (0.53) | UBE2MDCUN1D1MEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |