Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | IDH2 | P48735 | 2/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.43 |
| ▸ | UBE2M | P61081 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17206619 | 0.91 | EPHX2 (0.48) | EPHX2MAOAMAOBLMNAIDH2 | |
| SCHEMBL17206695 | 0.89 | EPHX2 (0.46) | EPHX2LMNAIDH2DCUN1D1UBE2M | |
| SCHEMBL17206628 | 0.87 | MEN1 (0.45) | EPHX2LMNAMEN1KMT2ASMYD3 | |
| SCHEMBL17206682 | 0.87 | TRPV4 (0.48) | EPHX2LMNAIDH2DCUN1D1UBE2M | |
| SCHEMBL9924143 | 0.87 | EPHX2 (0.44) | EPHX2LMNAIDH2DCUN1D1UBE2M | |
| SCHEMBL9924134 | 0.86 | MAPT (0.46) | EPHX2LMNAIDH2DCUN1D1UBE2M | |
| SCHEMBL9924226 | 0.82 | EPHX2 (0.53) | EPHX2CCR2LMNAIDH2DCUN1D1 | |
| SCHEMBL9924227 | 0.81 | EPHX2 (0.52) | EPHX2MAOAMAOBLMNAIDH2 | |
| SCHEMBL17206706 | 0.81 | DCUN1D1 (0.52) | EPHX2LMNAIDH2DCUN1D1UBE2M | |
| SCHEMBL9924130 | 0.80 | DCUN1D1 (0.52) | EPHX2LMNAIDH2DCUN1D1UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |