Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924243 | 0.91 | P2RX7 (0.39) | P2RX7 | |
| SCHEMBL9924237 | 0.90 | SIGMAR1 (0.39) | — | |
| SCHEMBL9924272 | 0.89 | P2RX7 (0.41) | P2RX7 | |
| SCHEMBL9924065 | 0.88 | P2RX7 (0.42) | P2RX7 | |
| SCHEMBL9924245 | 0.87 | EPHX2 (0.49) | P2RX7 | |
| SCHEMBL9924242 | 0.85 | LMNA (0.40) | — | |
| SCHEMBL9924268 | 0.85 | SSTR3 (0.46) | — | |
| SCHEMBL17206627 | 0.84 | KMT2A (0.42) | — | |
| SCHEMBL9924426 | 0.84 | EPHX1 (0.44) | — | |
| SCHEMBL9924269 | 0.84 | SSTR3 (0.45) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |