Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923858 | 0.92 | ALDH1A1 (0.41) | P2RX7 | |
| SCHEMBL9923859 | 0.91 | CHRM1 (0.41) | — | |
| SCHEMBL9924270 | 0.91 | HPGD (0.40) | P2RX7 | |
| SCHEMBL9924251 | 0.90 | CYP2D6 (0.41) | P2RX7CYP2D6PKMCYP2C19 | |
| SCHEMBL9924064 | 0.90 | CHRM1 (0.40) | P2RX7 | |
| SCHEMBL9924271 | 0.88 | P2RX7 (0.43) | P2RX7 | |
| SCHEMBL9924063 | 0.86 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL9924273 | 0.86 | CHRM1 (0.41) | — | |
| SCHEMBL9924274 | 0.86 | CHRM1 (0.41) | — | |
| SCHEMBL9924067 | 0.85 | SMN1; SMN2 (0.43) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |