Sugi Predict

Sugi Predict / Compounds / SCHEMBL9925463

SCHEMBL9925463

SCHEMBL9925463

Brc1oc2ccc3c(ccc4oc(Br)c(-c5ccccc5)c43)c2c1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CDK1 P06493 3/20 0.39
▸ CCNB1 P14635 3/20 0.39
▸ CCNE1 P24864 3/20 0.39
▸ CDK2 P24941 3/20 0.39
▸ CDK4 P11802 1/20 0.39
▸ CCND1 P24385 1/20 0.39
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ GABRP O00591 1/20 0.37
▸ GABRD O14764 1/20 0.37
▸ GABRA1 P14867 1/20 0.37
▸ GABRB1 P18505 1/20 0.37
▸ GABRG2 P18507 1/20 0.37
▸ GABRB3 P28472 1/20 0.37
▸ GABRA5 P31644 1/20 0.37
▸ GABRA3 P34903 1/20 0.37
▸ GABRA2 P47869 1/20 0.37
▸ GABRB2 P47870 1/20 0.37
▸ GABRA4 P48169 1/20 0.37
▸ GABRE P78334 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9925464 0.78 TNK2 (0.49) MEN1KMT2ACA1CA2CYP1B1
SCHEMBL11663639 0.78 CA1 (0.49) MEN1KMT2AGABRPGABRDGABRA1
SCHEMBL11546467 0.77 MEN1 (0.42) MEN1KMT2ACA1CA2CYP3A4
SCHEMBL10038095 0.75 KDM4E (0.49) KMT2ACYP1A2CYP1A1CYP1B1KDM4E
SCHEMBL10038193 0.75 NFKB1 (0.57) KMT2ACYP1A2CYP1A1CYP1B1CYP2C9
SCHEMBL19683687 0.73 CYP1A1 (0.40) CDK1CCNB1CA1CA2CYP1A2
SCHEMBL11435737 0.73 MEN1 (0.33) CDK1CCNB1CCNE1CDK2CDK4
SCHEMBL11547910 0.73 L3MBTL1 (0.53) MEN1KMT2ACYP1A2CYP1A1CYP1B1
SCHEMBL11544822 0.73 MAOB (0.42) MEN1KMT2ACYP1A2CYP2C9CYP2C19
SCHEMBL11624054 0.72 FABP4 (0.47) CA1KDM4EMAPTTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304595-A1 Electroactive Compounds LG CHEM, LTD. (KR) 2025-10-02 — — US disclosed
US-12384796-B2 Electroactive compounds LG CHEM, LTD. (KR) 2025-08-12 — — US disclosed
CN-109153684-B Electroactive compounds 株式会社LG化学 2021-12-21 — — CN disclosed
WO-2017210072-A1 ELECTROACTIVE COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2017-12-07 — — WO disclosed
WO-2017210072-A1 ELECTROACTIVE COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2017-12-07 — — WO disclosed
US-8247810-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2012-08-21 — — US disclosed
US-8247810-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2012-08-21 — — US disclosed
US-8216753-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2012-07-10 — — US disclosed
US-8216753-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2012-07-10 — — US disclosed
US-20120146013-A1 ELECTROACTIVE MATERIALS E I DU PONT DE NEMOURS AND COMPANY (US) 2012-06-14 — — US disclosed
US-20120146013-A1 ELECTROACTIVE MATERIALS E I DU PONT DE NEMOURS AND COMPANY (US) 2012-06-14 — — US disclosed
US-20090159877-A1 ELECTROACTIVE MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY 2009-06-25 — — US disclosed
US-20090159877-A1 ELECTROACTIVE MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY 2009-06-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304595-A1 Electroactive Compounds NAT1, NES, SULT1E1 CDK1 2679/4885CCNB1 2054/4885CCNE1 291/4885
US-12384796-B2 Electroactive compounds NES, NAT1, SCN1B CDK1 2596/4885CCNB1 1859/4885CCNE1 285/4885
US-20120146013-A1 ELECTROACTIVE MATERIALS RCOR3, KCNN4, MSRB3 CDK1 2216/4885CCNB1 2638/4885CCNE1 1583/4885
US-20090159877-A1 ELECTROACTIVE MATERIALS RCOR3, KCNN4, MSRB3 CDK1 2216/4885CCNB1 2638/4885CCNE1 1583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.