Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27808345 | 0.84 | LIPE (0.46) | TSPOESR1HPGDPAX8BRD4 | |
| SCHEMBL21084775 | 0.84 | PAX8 (0.46) | TSPOTSHRHSD17B10TDP1ALDH1A1 | |
| SCHEMBL11355173 | 0.80 | TSPO (0.65) | TSPOPTGS2TSHRKDM4EHSD17B10 | |
| SCHEMBL16738432 | 0.79 | TSPO (0.39) | TSPOKDM4ETDP1ALDH1A1PAX8 | |
| SCHEMBL20164280 | 0.79 | TSPO (0.44) | TSPOPTGS2TSHRKDM4EHSD17B10 | |
| SCHEMBL15054207 | 0.78 | GPBAR1 (0.42) | TSPOPAX8BRD4 | |
| SCHEMBL30416821 | 0.78 | TSPO (0.38) | TSPOKDM4ETDP1ALDH1A1PAX8 | |
| SCHEMBL12117478 | 0.78 | LIPE (0.43) | ALDH1A1SMN1; SMN2PAX8BRD4LIPE | |
| SCHEMBL27457875 | 0.77 | KDM4E (0.37) | TSPOKDM4EPAX8LMNABRD4 | |
| SCHEMBL22308521 | 0.77 | PTGS2 (0.53) | TSPOPTGS2TSHRKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011483-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-01-27 | — | — | WO | disclosed |