Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018111 | 0.86 | PAX8 (0.55) | RAB9AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL9343287 | 0.82 | CYP3A4 (0.51) | RAB9AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL3794822 | 0.81 | RAB9A (0.47) | RAB9AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL23407754 | 0.80 | RAB9A (0.54) | RAB9AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL14384381 | 0.80 | PAX8 (0.50) | RAB9AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL3364970 | 0.80 | PAX8 (0.50) | RAB9AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL7665673 | 0.79 | PAX8 (0.45) | RAB9AMEN1KMT2ANPSR1PAX8 | |
| SCHEMBL8970607 | 0.79 | SMN1; SMN2 (0.57) | RAB9ASMN1; SMN2NPC1ELANELMNA | |
| SCHEMBL25960279 | 0.78 | PAX8 (0.44) | RAB9AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL4015896 | 0.78 | PAX8 (0.49) | RAB9AMEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011483-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-01-27 | — | — | WO | disclosed |