Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 3/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22816955 | 0.96 | PAX8 (0.48) | PAX8RXRANR1H2NR1H3EPHX2 | |
| SCHEMBL8018111 | 0.85 | PAX8 (0.55) | PAX8RXRANR1H2NR1H3NPSR1 | |
| SCHEMBL7667615 | 0.81 | LMNA (0.49) | PAX8RXRANR1H2NR1H3NPSR1 | |
| SCHEMBL3427487 | 0.81 | EPHX2 (0.40) | EPHX2KMT2ATRPV1GPR119LIPE | |
| SCHEMBL3425497 | 0.81 | SERPINE1 (0.45) | EPHX2TRPV1GPR119HDAC3HDAC4 | |
| SCHEMBL1875890 | 0.80 | SERPINE1 (0.49) | EPHX2KMT2AGPBAR1TRPV1LIPE | |
| SCHEMBL15504635 | 0.80 | MAPT (0.57) | RXRANR1H2NR1H3EPHX2RAB9A | |
| SCHEMBL27915004 | 0.80 | GPBAR1 (0.43) | NR1H3EPHX2NPSR1MEN1RAB9A | |
| SCHEMBL11031222 | 0.80 | LIPE (0.43) | PAX8RXRANR1H2NR1H3GPR119 | |
| SCHEMBL992564 | 0.79 | RAB9A (0.50) | PAX8RXRANR1H2NR1H3NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369221-B1 | Thiazolobenzoheterocycles, preparation and medicines containing same | AVENTIS PHARMA S.A. (FR) | 2002-04-09 | — | — | US | disclosed |