Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | LGMN | Q99538 | 4/20 | 0.51 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901045 | 0.91 | CASP1 (0.56) | CTSKCASP1 | |
| SCHEMBL29946174 | 0.91 | CASP1 (0.56) | CTSKCASP1 | |
| SCHEMBL29397437 | 0.89 | REN (0.55) | CTSKPSMB8PSMB5PSMB9CAPN1 | |
| SCHEMBL20263591 | 0.89 | MME (0.59) | CTSKLGMNPSMB1MMEECE1 | |
| SCHEMBL19384748 | 0.89 | MME (0.59) | CTSKLGMNPSMB1MMEECE1 | |
| SCHEMBL24992811 | 0.89 | MME (0.59) | CTSKLGMNPSMB1MMEECE1 | |
| SCHEMBL20677213 | 0.89 | MME (0.59) | CTSKLGMNPSMB1MMEECE1 | |
| SCHEMBL14371944 | 0.89 | MME (0.59) | CTSKLGMNPSMB1MMEECE1 | |
| SCHEMBL28819863 | 0.88 | MME (0.60) | CTSKLGMNPSMB1MMEECE1 | |
| SCHEMBL28645693 | 0.88 | MME (0.60) | CTSKLGMNPSMB1MMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076985-A2 | GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-06-14 | — | — | WO | disclosed |