Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12332974 | 0.92 | — | — | |
| SCHEMBL2069523 | 0.76 | METAP2 (0.42) | APPMETAP2HDAC8 | |
| SCHEMBL75931 | 0.76 | METAP2 (0.42) | APPMETAP2HDAC8 | |
| SCHEMBL66792 | 0.76 | METAP2 (0.42) | APPMETAP2HDAC8 | |
| SCHEMBL14492415 | 0.76 | ALDH1A1 (0.50) | CYP1A1CYP1A2 | |
| SCHEMBL9925867 | 0.76 | ACHE (0.44) | — | |
| SCHEMBL14643579 | 0.76 | ALDH1A1 (0.50) | CYP1A1CYP1A2 | |
| SCHEMBL12334415 | 0.74 | ALDH1A1 (0.48) | METAP2 | |
| Water SCHEMBL9600645 | 0.73 | METAP2 (0.40) | APPMETAP2CYP1A1CYP1A2HDAC8 | |
| Water SCHEMBL9600843 | 0.73 | METAP2 (0.40) | APPMETAP2CYP1A1CYP1A2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067419-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-28 | — | — | WO | disclosed |