Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | GCK | P35557 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257972 | 0.87 | MAPT (0.48) | LMNAALDH1A1LYNGRM5GCK | |
| SCHEMBL24310884 | 0.85 | KDR (0.48) | ALDH1A1LYNGRM5GCKMAPT | |
| SCHEMBL18519134 | 0.84 | KDR (0.48) | LMNAMAPT | |
| SCHEMBL167783 | 0.84 | KDR (0.58) | ALDH1A1LYN | |
| SCHEMBL170730 | 0.84 | HSD17B1 (0.50) | LMNAALDH1A1LYNGRM5GCK | |
| SCHEMBL170881 | 0.84 | ALDH1A1 (0.45) | LMNAALDH1A1LYNGRM5GCK | |
| SCHEMBL9926365 | 0.83 | ALDH1A1 (0.44) | LMNAALDH1A1LYNGRM5GCK | |
| SCHEMBL8736453 | 0.77 | ALDH1A1 (0.53) | LMNAALDH1A1LYNMEN1KMT2A | |
| SCHEMBL23900111 | 0.77 | HRH3 (0.50) | LYNMEN1KMT2AGRM5 | |
| SCHEMBL6383415 | 0.77 | KDR (0.47) | ALDH1A1LYNMEN1KMT2AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636585-B2 | DIARYL UREAS WITH KINASE INHIBITING ACTIVITY | BAYER HEALTHCARE LLC (US) | 2012-06-13 | — | — | EP | disclosed |