Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168824 | 0.86 | P2RX3 (0.45) | — | |
| SCHEMBL9926359 | 0.84 | LMNA (0.50) | ALDH1A1LYNMAPTSMN1; SMN2LMNA | |
| SCHEMBL257972 | 0.83 | MAPT (0.48) | ALDH1A1LYNMAPTSMN1; SMN2LMNA | |
| SCHEMBL24310884 | 0.82 | KDR (0.48) | ALDH1A1LYNMAPTGRM5GCK | |
| SCHEMBL167783 | 0.81 | KDR (0.58) | ALDH1A1LYN | |
| SCHEMBL170730 | 0.81 | HSD17B1 (0.50) | ALDH1A1LYNMAPTSMN1; SMN2LMNA | |
| SCHEMBL9926365 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LYNMAPTSMN1; SMN2LMNA | |
| SCHEMBL2643034 | 0.78 | UHRF1 (0.43) | ALDH1A1MAPTSMN1; SMN2LMNATDP1 | |
| SCHEMBL30885027 | 0.78 | UHRF1 (0.43) | ALDH1A1MAPTSMN1; SMN2LMNATDP1 | |
| SCHEMBL31680842 | 0.78 | PTGS2 (0.50) | ALDH1A1SMN1; SMN2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426122-A1 | Methylene urea derivative as RAF kinasse inhibitors | Merck Patent GmbH (DE) | 2012-03-07 | — | — | EP | disclosed |