Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15516423 | 0.83 | LMNA (0.56) | MAPTHTTHPGDALDH1A1MAPK1 | |
| SCHEMBL9926528 | 0.83 | MAPT (0.62) | MAPTHTTHPGDALDH1A1MAPK1 | |
| SCHEMBL3205146 | 0.81 | ITGB3 (0.66) | MAPTHTTHPGDALDH1A1MAPK1 | |
| SCHEMBL11558469 | 0.81 | MAPT (0.64) | MAPTHTTHPGDALDH1A1ITGB3 | |
| SCHEMBL31139405 | 0.81 | ITGB3 (0.66) | MAPTHTTHPGDALDH1A1MAPK1 | |
| SCHEMBL4409648 | 0.80 | L3MBTL1 (0.45) | MAPTHTTHPGDALDH1A1HSD17B10 | |
| SCHEMBL11595858 | 0.80 | ALDH1A1 (0.52) | MAPTHTTALDH1A1HSD17B10HDAC3 | |
| Hydrochloric Acid SCHEMBL10912163 | 0.79 | ITGB3 (0.64) | MAPTHTTHPGDALDH1A1ITGB3 | |
| SCHEMBL23189083 | 0.78 | MAPT (0.60) | MAPTHTTHPGDALDH1A1ITGB3 | |
| SCHEMBL13948837 | 0.78 | MAPT (0.60) | MAPTHTTHPGDALDH1A1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149661-A1 | TETRA-SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR USE AS MDM2 AND/OR MDM4 MODULATORS | NOVARTIS AG (CH) | 2012-06-14 | — | — | US | disclosed |
| CN-100587001-C | Polyacetal resin composition | POLYPLASTICS CO | 2010-02-03 | — | — | CN | disclosed |
| CN-1878834-A | Polyacetal resin composition | POLYPLASTICS CO (JP) | 2006-12-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149661-A1 | TETRA-SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR USE AS MDM2 AND/OR MDM4 MODULATORS | MDM4, MDM2, TP53 | MAPT 582/4885HTT 82/4885HPGD 2850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.