SCHEMBL9927340

SCHEMBL9927340

Cc1ccc2c(c1)Oc1cc(C)ccc1S2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2A6 P11509 2/20 0.36
LMNA P02545 1/20 0.33
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TRPA1 O75762 1/20 0.32
ACHE P22303 2/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38661805 1.00 MAPT (0.36) MAPTCYP1A2CYP2A6LMNAALDH1A1
SCHEMBL1610442 0.92 MAPT (0.46) MAPTCYP1A2CYP2A6LMNAALDH1A1
SCHEMBL9507670 0.90 LMNA (0.39) MAPTCYP2A6LMNAALDH1A1KDM4E
SCHEMBL18199790 0.88 AHR (0.47) MAPTLMNAALDH1A1HTTMAOB
SCHEMBL1610505 0.81 MAPT (0.46) MAPTCYP1A2CYP2A6ALDH1A1KDM4E
SCHEMBL38660742 0.81 MAPT (0.46) MAPTCYP1A2CYP2A6ALDH1A1KDM4E
SCHEMBL13203013 0.77 KMT2A (0.41) MAPTCYP2A6LMNAALDH1A1KDM4E
SCHEMBL19155781 0.76 DRD2 (0.41) LMNAHPGDSMN1; SMN2
SCHEMBL23056712 0.75 TRPA1 (0.31) TRPA1
SCHEMBL15845332 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535605-B2 Electroluminesecent material, method for manufacturing the same and a luminesecent device with the electroluminesecent material WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2022-12-27 US disclosed
WO-2021160132-A1 HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海美悦生物科技发展有限公司 2021-08-19 WO disclosed
WO-2021036140-A1 ELECTROLUMINESCENT MATERIAL, PREPARATION METHOD OF ELECTROLUMINESCENT MATERIAL AND LIGHT-EMITTING DEVICE 武汉华星光电半导体显示技术有限公司 2021-03-04 WO disclosed
US-20120211082-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLAR CELL USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-23 US disclosed
US-20120211082-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLAR CELL USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-23 US disclosed
EP-2463929-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL USING SAME Mitsubishi Chemical Corporation (JP) 2012-06-13 EP disclosed
US-4243782-A POLYMERIZATION CATALYSTS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11535605-B2 Electroluminesecent material, method for manufacturing the same and a luminesecent device with the electroluminesecent material CYBA, ALG3, ACR MAPT 2200/4885CYP1A2 1984/4885CYP2A6 4473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.