Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3219346 | 0.80 | ALDH1A1 (0.51) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL3223391 | 0.76 | MAPT (0.76) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL17199295 | 0.69 | MEN1 (0.60) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL3213503 | 0.69 | PTGS2 (0.50) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL3226759 | 0.69 | NPC1 (0.55) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL3676457 | 0.67 | NPC1 (0.45) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL3219976 | 0.66 | KMT2A (0.44) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28748681 | 0.66 | MEN1 (0.59) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28748631 | 0.65 | MEN1 (0.59) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL27759239 | 0.65 | NPC1 (0.40) | MAPTKMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149741-A1 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA LIMITED (BS) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149741-A1 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SMN1; SMN2, ACVR2B, CPT1B | MAPT 4683/4885KMT2A 1777/4885NPC1 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.