Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.43 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552482 | 1.00 | KMT2A (0.60) | KMT2AL3MBTL1JAK1KDM1AMAOB | |
| SCHEMBL19051699 | 1.00 | KMT2A (0.60) | KMT2AL3MBTL1JAK1KDM1AMAOB | |
| SCHEMBL30404117 | 1.00 | KMT2A (0.60) | KMT2AL3MBTL1JAK1KDM1AMAOB | |
| SCHEMBL1552484 | 1.00 | KMT2A (0.60) | KMT2AL3MBTL1JAK1KDM1AMAOB | |
| SCHEMBL13520171 | 1.00 | KMT2A (0.60) | KMT2AL3MBTL1JAK1KDM1AMAOB | |
| SCHEMBL2378151 | 1.00 | KMT2A (0.60) | KMT2AL3MBTL1JAK1KDM1AMAOB | |
| SCHEMBL17304781 | 0.93 | KMT2A (0.65) | KMT2AL3MBTL1JAK1KDM1AMAOB | |
| SCHEMBL1815532 | 0.90 | KMT2A (0.65) | KMT2AL3MBTL1JAK1KDM1AMAOB | |
| SCHEMBL25263326 | 0.88 | KMT2A (0.60) | KMT2AL3MBTL1JAK1KDM1AMAOB | |
| SCHEMBL21166304 | 0.88 | KMT2A (0.60) | KMT2AL3MBTL1JAK1KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585240-A | Macrocyclic BCL6 degrading agents | 丹娜-法伯癌症研究院 | 2025-03-07 | — | — | CN | disclosed |
| EP-3484871-B1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-4186897-A1 | PYRIDINECARBOXAMIDE COMPOUND USEFUL AS PIM KINASE INHIBITOR | Incyte Holdings Corporation (US) | 2023-05-31 | — | — | EP | disclosed |
| US-20230062491-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | MEDIC LIFE SCIENCES, INC. | 2023-03-02 | — | — | US | disclosed |
| EP-3670506-B1 | THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE HOLDINGS CORP (US) | 2023-01-04 | — | — | EP | disclosed |
| CN-108715590-B | Thiazolecarboxamide and picolinamide compounds useful as PIM kinase inhibitors | 因赛特公司 | 2022-03-08 | — | — | CN | disclosed |
| US-11229631-B2 | Thiazolecarboxamides and pyridinecarboxamide compounds useful as Pim kinase inhibitors | INCYTE CORPORATION (US) | 2022-01-25 | — | — | US | disclosed |
| US-11229631-B2 | Thiazolecarboxamides and pyridinecarboxamide compounds useful as Pim kinase inhibitors | INCYTE CORPORATION (US) | 2022-01-25 | — | — | US | disclosed |
| US-20200405702-A1 | THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION | 2020-12-31 | — | — | US | disclosed |
| US-10828290-B2 | Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors | INCYTE CORPORATION (US) | 2020-11-10 | — | — | US | disclosed |
| US-20140200227-A1 | THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION (US) | 2014-07-17 | — | — | US | disclosed |
| US-20140200216-A1 | BICYCLIC AROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION (US) | 2014-07-17 | — | — | US | disclosed |
| WO-2014110574-A1 | BICYCLIC AROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION (US) | 2014-07-17 | — | — | WO | disclosed |
| US-8211909-B2 | Treatment of antibiotic-resistant bacteria infection | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2012-07-03 | — | — | US | disclosed |
| US-20120157492-A1 | ANTIBIOTIC DRUG | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2012-06-21 | — | — | US | disclosed |
| US-20120157492-A1 | ANTIBIOTIC DRUG | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2012-06-21 | — | — | US | disclosed |
| US-20100041697-A1 | PNEUMONIA TREATMENT | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2010-02-18 | — | — | US | disclosed |
| WO-2010009014-A2 | ANTIBIOTIC DRUG | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2010-01-21 | — | — | WO | disclosed |
| US-20100004282-A1 | TREATMENT OF ANTIBIOTIC-RESISTANT BACTERIA INFECTION | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2010-01-07 | — | — | US | disclosed |
| WO-2010002965-A2 | PNEUMONIA TREATMENT | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2010-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200216-A1 | BICYCLIC AROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | PIM1, PIM2, PIM3 | KMT2A 417/4885L3MBTL1 1607/4885JAK1 273/4885 |
| US-20120157492-A1 | ANTIBIOTIC DRUG | MAL2, ME1, ACE | KMT2A 2063/4885L3MBTL1 1506/4885JAK1 922/4885 |
| US-20200405702-A1 | THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | PIM2, PIM1, PIM3 | KMT2A 732/4885L3MBTL1 1430/4885JAK1 47/4885 |
| US-20100041697-A1 | PNEUMONIA TREATMENT | NQO2, IFNG, PML | KMT2A 2415/4885L3MBTL1 2713/4885JAK1 3294/4885 |
| US-11229631-B2 | Thiazolecarboxamides and pyridinecarboxamide compounds useful as Pim kinase inhibitors | PIM2, PIM1, PIM3 | KMT2A 732/4885L3MBTL1 1430/4885JAK1 47/4885 |
| US-20230062491-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CDK9 | KMT2A 1277/4885L3MBTL1 2140/4885JAK1 218/4885 |
| US-10828290-B2 | Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors | PIM2, PIM1, PIM3 | KMT2A 732/4885L3MBTL1 1430/4885JAK1 47/4885 |
| US-20100004282-A1 | TREATMENT OF ANTIBIOTIC-RESISTANT BACTERIA INFECTION | MRPL19, FOSB, MGAM | KMT2A 3532/4885L3MBTL1 2423/4885JAK1 1807/4885 |
| US-20140200227-A1 | THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | PIM2, PIM1, PIM3 | KMT2A 732/4885L3MBTL1 1430/4885JAK1 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.