Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14504422 | 0.82 | MMP8 (0.43) | MMP8ALDH1A1LMNAHSD17B10PKM | |
| SCHEMBL12552335 | 0.80 | MMP8 (0.46) | MMP8ALDH1A1LMNAHSD17B10PKM | |
| SCHEMBL954289 | 0.77 | MMP8 (0.43) | MMP8ALDH1A1LMNAHSD17B10PKM | |
| SCHEMBL30032517 | 0.77 | POLB (0.41) | MMP8ALDH1A1LMNAHSD17B10PKM | |
| SCHEMBL235893 | 0.76 | MMP8 (0.46) | MMP8ALDH1A1LMNAHSD17B10PKM | |
| SCHEMBL27889607 | 0.75 | ALDH1A1 (0.48) | MMP8ALDH1A1LMNAHSD17B10PKM | |
| SCHEMBL4392350 | 0.75 | ALDH1A1 (0.48) | MMP8ALDH1A1LMNAHSD17B10PKM | |
| SCHEMBL1979744 | 0.75 | ALDH1A1 (0.48) | MMP8ALDH1A1LMNAHSD17B10PKM | |
| SCHEMBL60813 | 0.75 | — | — | |
| SCHEMBL29321227 | 0.75 | MMP8 (0.50) | MMP8ALDH1A1LMNAHSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103403038-B | Carbon monoxide-olefin polymeric and polymer prepared therefrom with electron donor in halo malonate | 格雷斯公司 | 2017-10-31 | — | — | CN | claimed |
| US-8697827-B2 | Catalyst composition with halo-malonate internal electron donor and polymer from same | W. R. GRACE & CO.-CONN (US) | 2014-04-15 | — | — | US | claimed |
| CN-103403038-A | Catalyst composition with halo-malonate internal electron donor and polymer from same | DOW GLOBAL TECHNOLOGIES INC | 2013-11-20 | — | — | CN | claimed |
| EP-2655434-A1 | CATALYST COMPOSITION WITH HALO-MALONATE INTERNAL ELECTRON DONOR AND POLYMER FROM SAME | Dow Global Technologies LLC (US) | 2013-10-30 | — | — | EP | claimed |
| US-20130150234-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-13 | — | — | US | claimed |
| US-8383540-B2 | Catalyst composition with halo-malonate internal electron donor and polymer from same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-02-26 | — | — | US | claimed |
| WO-2012087535-A1 | CATALYST COMPOSITION WITH HALO-MALONATE INTERNAL ELECTRON DONOR AND POLYMER FROM SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-06-28 | — | — | WO | claimed |
| US-20120157296-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | W. R. GRACE & CO.-CONN. | 2012-06-21 | — | — | US | claimed |
| CN-103403038-B | Carbon monoxide-olefin polymeric and polymer prepared therefrom with electron donor in halo malonate | 格雷斯公司 | 2017-10-31 | — | — | CN | disclosed |
| US-8697827-B2 | Catalyst composition with halo-malonate internal electron donor and polymer from same | W. R. GRACE & CO.-CONN (US) | 2014-04-15 | — | — | US | disclosed |
| EP-2655434-A1 | CATALYST COMPOSITION WITH HALO-MALONATE INTERNAL ELECTRON DONOR AND POLYMER FROM SAME | Dow Global Technologies LLC (US) | 2013-10-30 | — | — | EP | disclosed |
| US-20130150234-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-13 | — | — | US | disclosed |
| US-20130150234-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-13 | — | — | US | disclosed |
| US-20130150234-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-13 | — | — | US | disclosed |
| US-8383540-B2 | Catalyst composition with halo-malonate internal electron donor and polymer from same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-02-26 | — | — | US | disclosed |
| WO-2012087535-A1 | CATALYST COMPOSITION WITH HALO-MALONATE INTERNAL ELECTRON DONOR AND POLYMER FROM SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| US-20120157296-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | W. R. GRACE & CO.-CONN. | 2012-06-21 | — | — | US | disclosed |
| US-20120157434-A1 | Antimicrobial heterocyclic compounds for treatment of bacterial infections | CSO of MicuRx Pharmaceuticals, Inc. | 2012-06-21 | — | — | US | disclosed |
| US-20120157296-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | W. R. GRACE & CO.-CONN. | 2012-06-21 | — | — | US | disclosed |
| US-20120157296-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | W. R. GRACE & CO.-CONN. | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157434-A1 | Antimicrobial heterocyclic compounds for treatment of bacterial infections | NISCH, NOD1, NQO1 | MMP8 79/4885ALDH1A1 953/4885LMNA 2201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.