Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28643501 | 0.76 | ALOX5 (0.43) | CES2CES1KEAP1GAAKMT2A | |
| SCHEMBL5247902 | 0.70 | CES2 (0.42) | SLC6A2SLC6A4SLC6A3CES2CES1 | |
| SCHEMBL5247893 | 0.69 | CES2 (0.41) | SLC6A2SLC6A4SLC6A3CES2CES1 | |
| SCHEMBL914754 | 0.69 | CYP2C19 (0.51) | GAACYP2C19HTTKMT2A | |
| SCHEMBL4640223 | 0.68 | ALOX5 (0.42) | SLC6A2SLC6A4SLC6A3CES2CES1 | |
| Hydrochloric Acid SCHEMBL5286030 | 0.66 | ALOX5 (0.41) | SLC6A2SLC6A4SLC6A3CES2CES1 | |
| SCHEMBL2461302 | 0.66 | GSR (0.47) | CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3898505 | 0.66 | CACNA2D1 (0.47) | CACNA2D1ALOX5 | |
| SCHEMBL3898507 | 0.66 | CACNA2D1 (0.47) | CACNA2D1ALOX5 | |
| SCHEMBL3229012 | 0.66 | NPC1 (0.53) | SLC6A2SLC6A4SLC6A3CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8728326-B2 | Polymer and methods for preparing and using the same | GENERAL ELECTRIC COMPANY (US) | 2014-05-20 | — | — | US | disclosed |
| US-20120152851-A1 | POLYMER AND METHODS FOR PREPARING AND USING THE SAME | BL TECHNOLOGIES, INC. | 2012-06-21 | — | — | US | disclosed |
| WO-2012082400-A2 | POLYMER AND METHODS FOR PREPARING AND USING THE SAME | GENERAL ELECTRIC COMPANY (US) | 2012-06-21 | — | — | WO | disclosed |