Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5247893 | 0.88 | CES2 (0.41) | CES2CES1KEAP1ALOX5SLC6A2 | |
| SCHEMBL5915082 | 0.74 | CACNA2D1 (0.45) | ALOX5ALDH1A1LMNAPOLB | |
| SCHEMBL5914999 | 0.74 | CACNA2D1 (0.45) | ALOX5ALDH1A1LMNAPOLB | |
| SCHEMBL4215659 | 0.70 | GLS (0.48) | CES2CES1KEAP1ALOX5GLS | |
| Bicarbonate SCHEMBL5247907 | 0.70 | CES2 (0.49) | CES2CES1KEAP1ALOX5GLS | |
| SCHEMBL9931140 | 0.70 | SLC6A2 (0.36) | CES2CES1KEAP1ALOX5SLC6A2 | |
| SCHEMBL6453628 | 0.70 | HSD17B2 (0.42) | CES2CES1KEAP1ALOX5CYP2C19 | |
| SCHEMBL6451012 | 0.69 | FFAR1 (0.41) | CES2CES1KEAP1ALOX5CYP2C19 | |
| SCHEMBL5245778 | 0.69 | — | — | |
| SCHEMBL2251571 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406605-B1 | CARBAMATES OF 2-HETEROCYCLIC-1,2-ETHANEDIOLS | SK CORP (KR) | 2007-09-19 | — | — | EP | disclosed |
| US-20050065193-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | SK CORPORATION | 2005-03-24 | — | — | US | disclosed |
| US-6841569-B2 | Carbamates of 2-heterocyclic-1,2-ethanediols | SK CORPORATION (US) | 2005-01-11 | — | — | US | disclosed |
| US-20030078235-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065193-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | CNR2, CNR1, GRIN2C | CES2 8/4885CES1 159/4885KEAP1 2923/4885 |
| US-20030078235-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | CNR2, CNR1, GRIN2C | CES2 8/4885CES1 159/4885KEAP1 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.