Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9931139 | 0.78 | CYP2C19 (0.47) | CYP2C19RAB9APSMB5CTSCSLC1A3 | |
| SCHEMBL28050463 | 0.76 | NPC1 (0.39) | CYP2C19RAB9AALDH1A1TSHRPOLB | |
| SCHEMBL28643501 | 0.76 | ALOX5 (0.43) | RAB9AALDH1A1TSHRPOLBNPC1 | |
| SCHEMBL7270401 | 0.76 | NPC1 (0.49) | CYP2C19RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL16486014 | 0.73 | CYP1A2 (0.46) | PKM | |
| SCHEMBL28643500 | 0.73 | THRB (0.51) | CYP2C19RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27923709 | 0.72 | CYP2C19 (0.51) | CYP2C19RAB9ACTSCSLC1A3SLC1A2 | |
| SCHEMBL27772992 | 0.72 | CYP2C19 (0.51) | CYP2C19RAB9ACTSCSLC1A3SLC1A2 | |
| SCHEMBL7270476 | 0.71 | CYP2C19 (0.64) | CYP2C19RAB9ACTSCSLC1A3SLC1A2 | |
| SCHEMBL9015298 | 0.71 | TSHR (0.58) | CYP2C19RAB9AALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312290-B2 | Curable formulations, cured compositions, and articles derived thereform | GENERAL ELECTRIC COMPANY (US) | 2007-12-25 | — | — | US | claimed |
| EP-1799728-A1 | CURABLE FORMULATIONS, CURED COMPOSITIONS, AND ARTICLES DERIVED THEREFROM | General Electric Company (US) | 2007-06-27 | — | — | EP | claimed |
| WO-2006036489-A1 | CURABLE FORMULATIONS, CURED COMPOSITIONS, AND ARTICLES DERIVED THEREFORM | GENERAL ELECTRIC COMPANY (US) | 2006-04-06 | — | — | WO | claimed |
| US-20060069222-A1 | Curable formulations, cured compositions, and articles derived thereform | GENERAL ELECTRIC COMPANY | 2006-03-30 | — | — | US | claimed |
| EP-1984318-B1 | HIGH REFRACTIVE INDEX MONOMERS AND (CO)POLYMERS PREPARED THEREFROM | OCULENTIS HOLDING BV (NL) | 2015-08-26 | — | — | EP | disclosed |
| US-9103964-B2 | Intraocular lenses essentially free from glistenings | OCULENTIS HOLDING B.V. (NL) | 2015-08-11 | — | — | US | disclosed |
| US-8216357-B2 | Protective coating compositions and devices | GENERAL ELECTRIC COMPANY (US) | 2012-07-10 | — | — | US | disclosed |
| US-7923520-B2 | High refractive index monomers and (co)polymers prepared therefrom | PROCORNEA HOLDING B.V. (NL) | 2011-04-12 | — | — | US | disclosed |
| US-20110073171-A1 | PROTECTIVE COATING COMPOSITIONS AND DEVICES | GENERAL ELECTRIC COMPANY (US) | 2011-03-31 | — | — | US | disclosed |
| EP-2302006-A1 | Protective coating compositions and devices | General Electric Company (US) | 2011-03-30 | — | — | EP | disclosed |
| EP-1984761-B1 | INTRAOCULAR LENSES ESSENTIALLY FREE FROM GLISTENINGS | PROCORNEA HOLDING BV (NL) | 2011-03-23 | — | — | EP | disclosed |
| US-20110021733-A1 | INTRAOCULAR LENSES ESSENTIALLY FREE FROM GLISTENINGS | PROCORNEA HOLDING B.V. | 2011-01-27 | — | — | US | disclosed |
| US-20090054978-A1 | INTRAOCULAR LENSES ESSENTIALLY FREE FROM GLISTENINGS | PROCOMEA HOLDING B.V. | 2009-02-26 | — | — | US | disclosed |
| US-20090023879-A1 | HIGH REFRACTIVE INDEX MONOMERS AND (CO)POLYMERS PREPARED THEREFROM | PROCORNEA HOLDING B.V. | 2009-01-22 | — | — | US | disclosed |
| US-7312290-B2 | Curable formulations, cured compositions, and articles derived thereform | GENERAL ELECTRIC COMPANY (US) | 2007-12-25 | — | — | US | disclosed |
| US-7271283-B2 | High refractive index, UV-curable monomers and coating compositions prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 2007-09-18 | — | — | US | disclosed |
| EP-1818690-A1 | Intraocular lenses essentially free from glistenings | Procornea Holding B.V. (NL) | 2007-08-15 | — | — | EP | disclosed |
| US-20060069222-A1 | Curable formulations, cured compositions, and articles derived thereform | GENERAL ELECTRIC COMPANY | 2006-03-30 | — | — | US | disclosed |
| EP-1512704-A1 | High refractive index, UV-curable monomers and coating compositions prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 2005-03-09 | — | — | EP | disclosed |
| US-20050049376-A1 | High refractive index, uv-curable monomers and coating compositions prepared therefrom | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023879-A1 | HIGH REFRACTIVE INDEX MONOMERS AND (CO)POLYMERS PREPARED THEREFROM | MACF1, FHIT, ALOX5 | CYP2C19 2364/4885RAB9A 2529/4885PSMB5 788/4885 |
| US-20050049376-A1 | High refractive index, uv-curable monomers and coating compositions prepared therefrom | MACF1, WASF2, THEM6 | CYP2C19 2659/4885RAB9A 2801/4885PSMB5 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.