Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559657 | 0.80 | TRPA1 (0.34) | TRPA1 | |
| SCHEMBL56321 | 0.80 | TRPA1 (0.36) | TRPA1 | |
| SCHEMBL15412274 | 0.77 | TRPA1 (0.37) | TRPA1 | |
| SCHEMBL1665854 | 0.76 | TRPA1 (0.40) | TRPA1 | |
| SCHEMBL783208 | 0.76 | TRPA1 (0.36) | TRPA1 | |
| SCHEMBL28229215 | 0.75 | TRPA1 (0.37) | TRPA1 | |
| Ethylene Glycol SCHEMBL28328525 | 0.75 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL9931933 | 0.75 | PRKCA (0.30) | — | |
| SCHEMBL18918974 | 0.75 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL9443286 | 0.74 | ALDH1A1 (0.35) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2652050-B1 | WATERBORNE COATING COMPOSITIONS THAT INCLUDE 2,2,4-TRIMETHYL-3-OXOPENTANOATE ESTERS AS REACTIVE COALESCENTS | EASTMAN CHEM CO (US) | 2018-10-17 | — | — | EP | claimed |
| CN-103237851-B | Including 2,2,4 trimethyl 3 oxopentanoic acid esters as the water-based paint compositions of coalescence reactive agent | 伊士曼化工公司 | 2016-12-21 | — | — | CN | claimed |
| US-9029451-B2 | Waterborne coating compositions that include 2,2,4-trimethyl-3-oxopentanoate esters as reactive coalescents | EASTMAN CHEMICAL COMPANY (US) | 2015-05-12 | — | — | US | claimed |
| EP-2652050-A1 | WATERBORNE COATING COMPOSITIONS THAT INCLUDE 2,2,4-TRIMETHYL-3-OXOPENTANOATE ESTERS AS REACTIVE COALESCENTS | Eastman Chemical Company (US) | 2013-10-23 | — | — | EP | claimed |
| US-20120157614-A1 | WATERBORNE COATING COMPOSITIONS THAT INCLUDE 2,2,4-TRIMETHYL-3-OXOPENTANOATE ESTERS AS REACTIVE COALESCENTS | EASTMAN CHEMICAL COMPANY (US) | 2012-06-21 | — | — | US | claimed |
| WO-2012082512-A1 | WATERBORNE COATING COMPOSITIONS THAT INCLUDE 2,2,4-TRIMETHYL-3-OXOPENTANOATE ESTERS AS REACTIVE COALESCENTS | EASTMAN CHEMICAL COMPANY (US) | 2012-06-21 | — | — | WO | claimed |
| EP-2652050-B1 | WATERBORNE COATING COMPOSITIONS THAT INCLUDE 2,2,4-TRIMETHYL-3-OXOPENTANOATE ESTERS AS REACTIVE COALESCENTS | EASTMAN CHEM CO (US) | 2018-10-17 | — | — | EP | disclosed |
| US-9029451-B2 | Waterborne coating compositions that include 2,2,4-trimethyl-3-oxopentanoate esters as reactive coalescents | EASTMAN CHEMICAL COMPANY (US) | 2015-05-12 | — | — | US | disclosed |
| EP-2652050-A1 | WATERBORNE COATING COMPOSITIONS THAT INCLUDE 2,2,4-TRIMETHYL-3-OXOPENTANOATE ESTERS AS REACTIVE COALESCENTS | Eastman Chemical Company (US) | 2013-10-23 | — | — | EP | disclosed |
| US-20120157614-A1 | WATERBORNE COATING COMPOSITIONS THAT INCLUDE 2,2,4-TRIMETHYL-3-OXOPENTANOATE ESTERS AS REACTIVE COALESCENTS | EASTMAN CHEMICAL COMPANY (US) | 2012-06-21 | — | — | US | disclosed |
| WO-2012082512-A1 | WATERBORNE COATING COMPOSITIONS THAT INCLUDE 2,2,4-TRIMETHYL-3-OXOPENTANOATE ESTERS AS REACTIVE COALESCENTS | EASTMAN CHEMICAL COMPANY (US) | 2012-06-21 | — | — | WO | disclosed |