Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1814483 | 0.80 | HTT (0.48) | MEN1KMT2AHTTBACE1LMNA | |
| SCHEMBL16704916 | 0.80 | MEN1 (0.30) | MEN1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL9932870 | 0.79 | PDK2 (0.35) | PGRMEN1KMT2AKDM4EESR1 | |
| SCHEMBL9934689 | 0.74 | ABCB11 (0.41) | PGRMEN1KMT2AHTTLMNA | |
| SCHEMBL9932915 | 0.74 | BACE1 (0.42) | PGRMEN1KMT2AHTTBACE1 | |
| SCHEMBL9931978 | 0.74 | BACE1 (0.42) | PGRMEN1KMT2AHTTBACE1 | |
| SCHEMBL1814669 | 0.68 | HTT (0.43) | KMT2AHTTBACE1LMNAALDH1A1 | |
| SCHEMBL16713272 | 0.67 | KDM4E (0.35) | HTTLMNAMAPTKDM4EHSD17B10 | |
| SCHEMBL9940214 | 0.66 | MAOA (0.31) | — | |
| SCHEMBL9933463 | 0.65 | PDK2 (0.34) | MEN1KMT2AALDH1A1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073838-B2 | Method of making indeno-fused naphthol materials | TRANSITIONS OPTICAL, INC. (US) | 2015-07-07 | — | — | US | disclosed |
| US-20140364618-A1 | Method of Making Indeno-Fused Naphthol Materials | TRANSITIONS OPTICALS, INC. (US) | 2014-12-11 | — | — | US | disclosed |
| US-8765978-B2 | Method of making indeno-fused naphthol materials | TRANSITIONS OPTICAL, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| WO-2012082837-A1 | METHOD OF MAKING INDENO-FUSED NAPHTHOL MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20120157696-A1 | METHOD OF MAKING INDENO-FUSED NAPHTHOL MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364618-A1 | Method of Making Indeno-Fused Naphthol Materials | IDH3A, NQO1, IDH3B | PGR 128/4885MEN1 595/4885KMT2A 1373/4885 |
| US-20120157696-A1 | METHOD OF MAKING INDENO-FUSED NAPHTHOL MATERIALS | NQO1, IDH3A, IDH2 | PGR 263/4885MEN1 903/4885KMT2A 1788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.