SCHEMBL993265

SCHEMBL993265

O=C(O)CNC(=O)[C@H](CS)NC(=O)CC[C@H](NCO)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.69
GSTK1 Q9Y2Q3 1/20 0.69
GLO1 Q04760 5/20 0.48
FOLH1 Q04609 2/20 0.44
NOD1 Q9Y239 2/20 0.38
ACE P12821 1/20 0.36
FNTA P49354 2/20 0.36
FNTB P49356 2/20 0.36
PGGT1B P53609 1/20 0.36
MAPT P10636 2/20 0.36
PTGS2 P35354 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
RIMKLA Q8IXN7 1/20 0.36
NAALAD2 Q9Y3Q0 1/20 0.36
KDM4E B2RXH2 1/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36
NFKB1 P19838 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1332941 0.93 PTGS1 (0.71) PTGS1GSTK1GLO1FOLH1NOD1
SCHEMBL28862930 0.93 PTGS1 (0.71) PTGS1GSTK1GLO1FOLH1NOD1
SCHEMBL1646531 0.90 PTGS1 (0.71) PTGS1GSTK1GLO1FOLH1NOD1
SCHEMBL28524138 0.90 PTGS1 (0.71) PTGS1GSTK1GLO1FOLH1NOD1
SCHEMBL28284657 0.89 PTGS1 (0.66) PTGS1GSTK1GLO1FOLH1NOD1
SCHEMBL4657012 0.89 PTGS1 (0.66) PTGS1GSTK1GLO1FOLH1NOD1
SCHEMBL3388604 0.89 PTGS1 (0.66) PTGS1GSTK1GLO1FOLH1NOD1
SCHEMBL28337837 0.89 PTGS1 (0.66) PTGS1GSTK1GLO1FOLH1NOD1
SCHEMBL28502763 0.89 PTGS1 (0.69) PTGS1GSTK1GLO1FOLH1NOD1
SCHEMBL29559136 0.89 PTGS1 (0.72) PTGS1GSTK1GLO1FOLH1NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606752-B Pichia formate auxotroph strain and preparation method and application thereof 江南大学 2024-08-13 CN claimed
EP-3661420-B1 SCAVENGER PROTEIN(S) FOR IMPROVED PRESERVATION OF ANALYTE DETECTION SENSOR(S) AND METHOD(S) OF USE THEREOF SIEMENS HEALTHCARE DIAGNOSTICS INC (US) 2023-08-23 EP claimed
US-11339419-B2 Scavenger protein(s) for improved preservation of analyte detection sensor(s) and method(s) of use thereof SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2022-05-24 US claimed
EP-3661420-A1 SCAVENGER PROTEIN(S) FOR IMPROVED PRESERVATION OF ANALYTE DETECTION SENSOR(S) AND METHOD(S) OF USE THEREOF Siemens Healthcare Diagnostics Inc. (US) 2020-06-10 EP claimed
US-20200140917-A1 SCAVENGER PROTEIN(S) FOR IMPROVED PRESERVATION OF ANALYTE DETECTION SENSOR(S) AND METHOD(S) OF USE THEREOF SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2020-05-07 US claimed
WO-2019027879-A1 SCAVENGER PROTEIN(S) FOR IMPROVED PRESERVATION OF ANALYTE DETECTION SENSOR(S) AND METHOD(S) OF USE THEREOF SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2019-02-07 WO claimed
US-8992945-B2 Supramacromolecular polymer complexes providing controlled nitric oxide release for healing wounds UNIVERSITY OF TORONTO (CA) 2015-03-31 US claimed
WO-2011003172-A1 CONTROLLED NITRIC OXIDE DELIVERY FROM AQUEOUS S-NITROSOTHIOL CONJUGATED POLYMERS AND THEIR COMPLEXES UNIVERSITY OF TORONTO (CA) 2011-01-13 WO claimed
US-20100303891-A1 SUPRAMACROMOLECULAR POLYMER COMPLEXES PROVIDING CONTROLLED NITRIC OXIDE RELEASE FOR HEALING WOUNDS UNIVERSITY OF TORONTO (CA) 2010-12-02 US claimed
EP-2201077-A1 SUPRAMACRQMOLECULAR POLYMER COMPLEXES PROVIDING CONTROLLED NITRIC OXIDE RELEASE FOR HEALING WOUNDS University of Toronto (CA) 2010-06-30 EP claimed
WO-2009026680-A1 SUPRAMACRQMOLECULAR POLYMER COMPLEXES PROVIDING CONTROLLED NITRIC OXIDE RELEASE FOR HEALING WOUNDS LEE PING I (CA) 2009-03-05 WO claimed
EP-1179055-A1 NOVEL PHYTOCHELATIN SYNTHASES AND USES THEREFOR THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2002-02-13 EP claimed
WO-2000071695-A1 NOVEL PHYTOCHELATIN SYNTHASES AND USES THEREFOR THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2000-11-30 WO claimed
EP-1015603-A2 NEW PLANT GENES RHONE-POULENC AGRICULTURE LTD. (GB) 2000-07-05 EP claimed
WO-1999014337-A2 NEW PLANT GENES RHONE-POULENC AGRICULTURE LIMITED (GB) 1999-03-25 WO claimed
EP-4692363-A1 METHOD FOR PRODUCING METHYL COMPOUND Mitsubishi Chemical Corporation (JP) 2026-02-11 EP disclosed
US-12529078-B2 Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis GENOMATICA, INC. (US) 2026-01-20 US disclosed
EP-1015603-A2 NEW PLANT GENES RHONE-POULENC AGRICULTURE LTD. (GB) 2000-07-05 EP disclosed
EP-0986955-A1 Conjugates of glutathione as signal molecules GSF-Forschungszentrum für Umwelt und Gesundheit GmbH (DE) 2000-03-22 EP disclosed
WO-1999014337-A2 NEW PLANT GENES RHONE-POULENC AGRICULTURE LIMITED (GB) 1999-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12529078-B2 Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis ALDOA, FDPS, DERA PTGS1 1671/4885GSTK1 998/4885GLO1 258/4885
US-20100303891-A1 SUPRAMACROMOLECULAR POLYMER COMPLEXES PROVIDING CONTROLLED NITRIC OXIDE RELEASE FOR HEALING WOUNDS NOS3, NOS1, NOS2 PTGS1 292/4885GSTK1 1644/4885GLO1 836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.