Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9883026 | 0.89 | ALDH1A1 (0.46) | ALDH1A1TSHRTHRB | |
| SCHEMBL20787032 | 0.77 | SMN1; SMN2 (0.33) | ALDH1A1TSHR | |
| SCHEMBL9933063 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRB | |
| SCHEMBL22206100 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRB | |
| SCHEMBL18022214 | 0.71 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL23627434 | 0.70 | TSHR (0.47) | ALDH1A1TSHRTHRB | |
| SCHEMBL10204653 | 0.70 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL14816289 | 0.68 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRB | |
| SCHEMBL14816334 | 0.68 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRB | |
| SCHEMBL14633722 | 0.68 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809447-B2 | Acetoacetate-functional monomers and their uses in coating compositions | EASTMAN CHEMICAL COMPANY (US) | 2014-08-19 | — | — | US | disclosed |
| EP-2651874-A1 | ACETOACETATE-FUNCTIONAL MONOMERS AND THEIR USES IN COATING COMPOSITIONS | Eastman Chemical Company (US) | 2013-10-23 | — | — | EP | disclosed |
| US-20120157610-A1 | ACETOACETATE-FUNCTIONAL MONOMERS AND THEIR USES IN COATING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2012-06-21 | — | — | US | disclosed |
| WO-2012082348-A1 | ACETOACETATE-FUNCTIONAL MONOMERS AND THEIR USES IN COATING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157610-A1 | ACETOACETATE-FUNCTIONAL MONOMERS AND THEIR USES IN COATING COMPOSITIONS | ACACA, AMD1, ACAT2 | ALDH1A1 17/4885TSHR 4616/4885THRB 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.