Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9934203 | 0.93 | TP53 (0.32) | — | |
| SCHEMBL9934587 | 0.91 | TP53 (0.31) | — | |
| SCHEMBL9934470 | 0.89 | PDK2 (0.32) | — | |
| SCHEMBL9934164 | 0.89 | PDE4D (0.32) | — | |
| SCHEMBL9932985 | 0.89 | KDM4E (0.31) | — | |
| SCHEMBL9933979 | 0.86 | TP53 (0.31) | — | |
| SCHEMBL9935187 | 0.86 | ALK (0.32) | — | |
| SCHEMBL9934040 | 0.85 | HTR6 (0.31) | PGR | |
| SCHEMBL25604114 | 0.85 | PGR (0.32) | PGR | |
| SCHEMBL9932623 | 0.85 | KDM4E (0.36) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073838-B2 | Method of making indeno-fused naphthol materials | TRANSITIONS OPTICAL, INC. (US) | 2015-07-07 | — | — | US | disclosed |
| US-9073838-B2 | Method of making indeno-fused naphthol materials | TRANSITIONS OPTICAL, INC. (US) | 2015-07-07 | — | — | US | disclosed |
| US-9073838-B2 | Method of making indeno-fused naphthol materials | TRANSITIONS OPTICAL, INC. (US) | 2015-07-07 | — | — | US | disclosed |
| US-20140364618-A1 | Method of Making Indeno-Fused Naphthol Materials | TRANSITIONS OPTICALS, INC. (US) | 2014-12-11 | — | — | US | disclosed |
| US-20140364618-A1 | Method of Making Indeno-Fused Naphthol Materials | TRANSITIONS OPTICALS, INC. (US) | 2014-12-11 | — | — | US | disclosed |
| US-20140364618-A1 | Method of Making Indeno-Fused Naphthol Materials | TRANSITIONS OPTICALS, INC. (US) | 2014-12-11 | — | — | US | disclosed |
| US-8765978-B2 | Method of making indeno-fused naphthol materials | TRANSITIONS OPTICAL, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-20120157696-A1 | METHOD OF MAKING INDENO-FUSED NAPHTHOL MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| WO-2012082837-A1 | METHOD OF MAKING INDENO-FUSED NAPHTHOL MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20120157696-A1 | METHOD OF MAKING INDENO-FUSED NAPHTHOL MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| WO-2012082837-A1 | METHOD OF MAKING INDENO-FUSED NAPHTHOL MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20120157696-A1 | METHOD OF MAKING INDENO-FUSED NAPHTHOL MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364618-A1 | Method of Making Indeno-Fused Naphthol Materials | IDH3A, NQO1, IDH3B | PGR 128/4885 |
| US-20120157696-A1 | METHOD OF MAKING INDENO-FUSED NAPHTHOL MATERIALS | NQO1, IDH3A, IDH2 | PGR 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.