Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950747 | 0.84 | ADORA2A (0.39) | ADORA2APIK3CG | |
| SCHEMBL9933420 | 0.78 | MEN1 (0.32) | — | |
| SCHEMBL9934296 | 0.75 | BRD4 (0.40) | — | |
| SCHEMBL9973906 | 0.73 | ADORA2A (0.36) | ADORA2A | |
| SCHEMBL14444112 | 0.68 | L3MBTL1 (0.38) | — | |
| SCHEMBL9935659 | 0.68 | PARP1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL7950506 | 0.66 | IDH1 (0.33) | — | |
| SCHEMBL14444097 | 0.62 | IDH1 (0.30) | — | |
| SCHEMBL18882839 | 0.61 | ADORA2A (0.39) | ADORA2A | |
| SCHEMBL9935445 | 0.60 | S100A4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157494-A1 | ISOINDOLYL COMPOUNDS | HARRIS III RALPH NEW (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157494-A1 | ISOINDOLYL COMPOUNDS | P2RX7, P2RX3, P2RX1 | ADORA2A 18/4885PIK3CG 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.