Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15389921 | 0.90 | SMN1; SMN2 (0.34) | RAB9ATRPM8SMN1; SMN2TSHRCYP2C19 | |
| SCHEMBL11870472 | 0.85 | HTR2A (0.39) | TRPM8SMN1; SMN2CYP2C19TDP1POLB | |
| Bromide SCHEMBL9934306 | 0.84 | HTR2A (0.38) | TRPM8SMN1; SMN2CYP2C19TDP1POLB | |
| Iodide SCHEMBL9933723 | 0.84 | HTR2A (0.38) | TRPM8SMN1; SMN2CYP2C19TDP1POLB | |
| Hydrochloric Acid SCHEMBL9934286 | 0.84 | TDP1 (0.41) | TRPM8SMN1; SMN2CYP2C19TDP1POLB | |
| SCHEMBL9933271 | 0.83 | RAB9A (0.39) | RAB9ASMN1; SMN2TSHRCYP2C19ESR1 | |
| SCHEMBL15389719 | 0.75 | HCAR2 (0.35) | RAB9ATSHRCYP2C19ESR1ALDH1A1 | |
| SCHEMBL27887905 | 0.73 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL6391995 | 0.73 | CYP2C19 (0.41) | SMN1; SMN2CYP2C19ESR1KDM4ETDP1 | |
| SCHEMBL6391998 | 0.73 | CYP2C19 (0.41) | SMN1; SMN2CYP2C19ESR1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9159352-B2 | Polishing liquid composition for magnetic disk substrate | KAO CORPORATION (JP) | 2015-10-13 | — | — | US | disclosed |
| US-20140001155-A1 | MANUFACTURING METHOD OF MAGNETIC DISK SUBSTRATE | KAO CORPORATION (JP) | 2014-01-02 | — | — | US | disclosed |
| US-20130309946-A1 | METHOD FOR MANUFACTURING MAGNETIC DISC SUBSTRATE | KAO CORPORATION (JP) | 2013-11-21 | — | — | US | disclosed |
| US-20120156968-A1 | POLISHING LIQUID COMPOSITION FOR MAGNETIC DISK SUBSTRATE | KAO CORPORATION (JP) | 2012-06-21 | — | — | US | disclosed |