Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15389719 | 0.88 | HCAR2 (0.35) | RAB9ATSHRALOX5CYP2C19ESR1 | |
| SCHEMBL1137366 | 0.84 | HTR2A (0.39) | ALOX5CYP2C19ALDH1A1TDP1 | |
| SCHEMBL9934658 | 0.83 | RAB9A (0.38) | RAB9ATSHRCYP2C19ESR1KDM4E | |
| Bromide SCHEMBL9933509 | 0.83 | HTR2A (0.38) | ALOX5CYP2C19ALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL1898617 | 0.83 | TDP1 (0.39) | ALOX5CYP2C19KMT2AALDH1A1MAPT | |
| Iodide SCHEMBL9934390 | 0.83 | HTR2A (0.38) | ALOX5CYP2C19ALDH1A1TDP1 | |
| SCHEMBL7166960 | 0.78 | ALOX5 (0.42) | RAB9ATSHRALOX5CYP2C19KDM4E | |
| SCHEMBL28754589 | 0.75 | MEN1 (0.41) | KMT2AMEN1 | |
| SCHEMBL7704844 | 0.74 | TSHR (0.39) | RAB9ATSHRALOX5CYP2C19ESR1 | |
| SCHEMBL15389921 | 0.73 | SMN1; SMN2 (0.34) | RAB9ATSHRCYP2C19ESR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9159352-B2 | Polishing liquid composition for magnetic disk substrate | KAO CORPORATION (JP) | 2015-10-13 | — | — | US | disclosed |
| US-20140001155-A1 | MANUFACTURING METHOD OF MAGNETIC DISK SUBSTRATE | KAO CORPORATION (JP) | 2014-01-02 | — | — | US | disclosed |
| US-20130309946-A1 | METHOD FOR MANUFACTURING MAGNETIC DISC SUBSTRATE | KAO CORPORATION (JP) | 2013-11-21 | — | — | US | disclosed |
| US-20120156968-A1 | POLISHING LIQUID COMPOSITION FOR MAGNETIC DISK SUBSTRATE | KAO CORPORATION (JP) | 2012-06-21 | — | — | US | disclosed |