Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 3/20 | 0.38 |
| ▸ | HRH1 known ✓ | P35367 | 3/20 | 0.38 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11870472 | 0.98 | HTR2A (0.39) | TDP1HTR2AHRH1LMNATRPM8 | |
| Iodide SCHEMBL9933723 | 0.96 | HTR2A (0.38) | TDP1HTR2AHRH1LMNATRPM8 | |
| Bromide SCHEMBL9934306 | 0.96 | HTR2A (0.38) | TDP1HTR2AHRH1LMNATRPM8 | |
| Hydrochloric Acid SCHEMBL17364017 | 0.84 | TDP1 (0.40) | TDP1HTR2AHRH1LMNATRPM8 | |
| SCHEMBL9934658 | 0.84 | RAB9A (0.38) | TDP1LMNATRPM8SMN1; SMN2CYP2C19 | |
| SCHEMBL22073549 | 0.82 | HTR2A (0.38) | TDP1HTR2AHRH1LMNATRPM8 | |
| SCHEMBL15389921 | 0.82 | SMN1; SMN2 (0.34) | TDP1LMNATRPM8SMN1; SMN2CYP2C19 | |
| SCHEMBL6391995 | 0.80 | CYP2C19 (0.41) | TDP1HTR2AHRH1SMN1; SMN2CYP2C19 | |
| SCHEMBL6391998 | 0.80 | CYP2C19 (0.41) | TDP1HTR2AHRH1SMN1; SMN2CYP2C19 | |
| Hydrochloric Acid SCHEMBL2455720 | 0.79 | MEN1 (0.45) | TDP1HTR2AHRH1LMNATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109266058-A | A kind of catalysis process and application method of aqueous inorganic nano paint | 湖南凯斯利新材料有限公司 | 2019-01-25 | — | — | CN | claimed |
| CN-106833776-B | Situ-formed graft is modified the method that lignite prepares slurries additive agent | 中国五环工程有限公司 | 2018-10-19 | — | — | CN | claimed |
| CN-106833776-A | The method that the modified lignite of situ-formed graft prepares slurries additive agent | 中国五环工程有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-101735076-B | Method for preparing high-purity cationic monomer diallyl ethylbenzylammonium chloride | UNIV HUNAN SCI & TECHNOLOGY | 2013-06-12 | — | — | CN | claimed |
| CN-101735076-A | Method for preparing high-purity cationic monomer diallyl ethylbenzylammonium chloride | UNIV HUNAN SCI & TECHNOLOGY | 2010-06-16 | — | — | CN | claimed |
| CN-112029027-B | Graphene composite cationic emulsion and preparation method thereof | 厦门捌斗新材料科技有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-112029027-A | Graphene composite cationic emulsion and preparation method thereof | 厦门捌斗新材料科技有限公司 | 2020-12-04 | — | — | CN | disclosed |
| CN-107075036-B | Polyacrylamide resin, papermaking additive and paper | HARIMA CHEMICALS, INC. (JP) | 2019-11-01 | — | — | CN | disclosed |
| CN-110003386-A | Polyacrylamide resin, additive for paper making and paper | 哈利玛化成株式会社 | 2019-07-12 | — | — | CN | disclosed |
| CN-109266058-A | A kind of catalysis process and application method of aqueous inorganic nano paint | 湖南凯斯利新材料有限公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-106833776-B | Situ-formed graft is modified the method that lignite prepares slurries additive agent | 中国五环工程有限公司 | 2018-10-19 | — | — | CN | disclosed |
| CN-107075036-A | Polyacrylamide resin, papermaking additive and paper | 哈利玛化成株式会社 | 2017-08-18 | — | — | CN | disclosed |
| CN-101735076-B | Method for preparing high-purity cationic monomer diallyl ethylbenzylammonium chloride | UNIV HUNAN SCI & TECHNOLOGY | 2013-06-12 | — | — | CN | disclosed |
| CN-101687698-B | Glass fiber sizing agent containing amphoteric polymer compound | NITTO BOSEKI CO LTD | 2012-08-01 | — | — | CN | disclosed |
| CN-102533220-A | Polishing composition for magnetic disk substrate | KAO CORP | 2012-07-04 | — | — | CN | disclosed |
| US-20120156968-A1 | POLISHING LIQUID COMPOSITION FOR MAGNETIC DISK SUBSTRATE | KAO CORPORATION (JP) | 2012-06-21 | — | — | US | disclosed |
| CN-101735076-A | Method for preparing high-purity cationic monomer diallyl ethylbenzylammonium chloride | UNIV HUNAN SCI & TECHNOLOGY | 2010-06-16 | — | — | CN | disclosed |
| CN-101735076-A | Method for preparing high-purity cationic monomer diallyl ethylbenzylammonium chloride | UNIV HUNAN SCI & TECHNOLOGY | 2010-06-16 | — | — | CN | disclosed |
| CN-101735076-A | Method for preparing high-purity cationic monomer diallyl ethylbenzylammonium chloride | UNIV HUNAN SCI & TECHNOLOGY | 2010-06-16 | — | — | CN | disclosed |
| CN-101687698-A | Glass fiber sizing agent containing amphoteric polymer compound | NITTO BOSEKI CO LTD | 2010-03-31 | — | — | CN | disclosed |