Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | VNN1 | O95497 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27635652 | 0.89 | PLA2G4B (0.64) | L3MBTL1PARP10NPC1PLK1ALDH1A1 | |
| SCHEMBL27635650 | 0.89 | L3MBTL1 (0.56) | KMT2ANPSR1L3MBTL1PARP10NPC1 | |
| SCHEMBL845348 | 0.86 | NPSR1 (0.79) | KMT2ANPSR1L3MBTL1PARP10NPC1 | |
| SCHEMBL4475347 | 0.86 | NPC1 (0.60) | NPC1RAB9AVNN1MAPTHDAC3 | |
| SCHEMBL2056242 | 0.86 | L3MBTL1 (0.67) | L3MBTL1PARP10LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3539826 | 0.84 | NPC1 (0.58) | NPC1RAB9AVNN1HDAC3HDAC1 | |
| SCHEMBL2016489 | 0.81 | VNN1 (0.63) | KMT2ANPSR1PARP10NPC1RAB9A | |
| SCHEMBL11042318 | 0.81 | KMT2A (0.67) | KMT2ANPSR1L3MBTL1PARP10NPC1 | |
| SCHEMBL4117918 | 0.80 | EPHX2 (0.76) | KMT2AL3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL2721728 | 0.79 | CA12 (0.59) | KMT2AL3MBTL1LMNAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2652552-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | Transitions Optical, Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012082299-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |