Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1980570 | 0.98 | HRH3 (0.30) | HRH3 | |
| SCHEMBL9936834 | 0.98 | — | — | |
| SCHEMBL1982911 | 0.89 | HRH3 (0.31) | HRH3 | |
| SCHEMBL17677098 | 0.81 | SYK (0.34) | HRH3 | |
| SCHEMBL17677109 | 0.80 | HRH3 (0.41) | HRH3 | |
| SCHEMBL15127627 | 0.80 | HCAR3 (0.34) | — | |
| SCHEMBL15127656 | 0.78 | AR (0.36) | HRH3 | |
| SCHEMBL10611794 | 0.72 | CHEK1 (0.33) | — | |
| SCHEMBL15545785 | 0.69 | CASP1 (0.35) | — | |
| SCHEMBL15127626 | 0.68 | CRHR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651386-A2 | DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER | L'Oréal (FR) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080289-A2 | DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |