Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15019276 | 0.92 | KDM4E (0.59) | SIGMAR1KDM4ERECQLTDP1HRH3 | |
| SCHEMBL15040817 | 0.92 | KDM4E (0.59) | SIGMAR1KDM4ERECQLTDP1HRH3 | |
| SCHEMBL15040812 | 0.92 | KDM4E (0.59) | SIGMAR1KDM4ERECQLTDP1HRH3 | |
| SCHEMBL5217666 | 0.84 | LTA4H (0.62) | SIGMAR1KDM4EKMT2A | |
| SCHEMBL2249200 | 0.83 | LTA4H (0.68) | KDM4EHRH3 | |
| SCHEMBL4475207 | 0.82 | MCHR1 (0.77) | SIGMAR1HRH3HRH2HRH1 | |
| SCHEMBL225017 | 0.82 | PSMB1 (0.69) | KDM4EHRH3 | |
| SCHEMBL27593 | 0.82 | PSMB1 (0.69) | KDM4EHRH3 | |
| SCHEMBL19234679 | 0.82 | SIGMAR1 (0.73) | SIGMAR1KDM4ERECQLTDP1HRH3 | |
| SCHEMBL23366756 | 0.81 | SIGMAR1 (0.71) | SIGMAR1KDM4ERECQLTDP1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |