Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9942183 | 0.92 | GCGR (0.55) | LTA4HGCGROPRK1 | |
| SCHEMBL9942716 | 0.91 | LTA4H (0.55) | LTA4HGCGROPRK1 | |
| SCHEMBL9940284 | 0.91 | OPRK1 (0.55) | LTA4HKDM4EGCGROPRK1 | |
| SCHEMBL9942788 | 0.91 | OPRK1 (0.55) | LTA4HKDM4EGCGROPRK1 | |
| SCHEMBL9966815 | 0.88 | ESR2 (0.54) | LTA4HKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9940164 | 0.88 | KDM4E (0.52) | LTA4HKDM4EALDH1A1GCGROPRK1 | |
| SCHEMBL9967009 | 0.87 | LTA4H (0.58) | LTA4HCNR1CNR2KDM4ETSHR | |
| SCHEMBL9940254 | 0.86 | LTA4H (0.57) | LTA4HCNR1CNR2TSHRNPSR1 | |
| SCHEMBL9966990 | 0.85 | LTA4H (0.54) | LTA4HCNR1CNR2ALDH1A1TSHR | |
| SCHEMBL9936264 | 0.85 | LTA4H (0.54) | LTA4HCNR1CNR2TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |