Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | GCGR | P47871 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 7/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.51 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9942788 | 1.00 | OPRK1 (0.55) | OPRK1GCGRLTA4HPSMB1PSMB5 | |
| SCHEMBL9942183 | 0.99 | GCGR (0.55) | OPRK1GCGRLTA4HPSMB1PSMB5 | |
| SCHEMBL9942716 | 0.92 | LTA4H (0.55) | OPRK1GCGRLTA4HHRH3 | |
| SCHEMBL9936164 | 0.91 | LTA4H (0.54) | OPRK1GCGRLTA4HKDM4E | |
| SCHEMBL9940164 | 0.90 | KDM4E (0.52) | OPRK1GCGRLTA4HHRH3KDM4E | |
| SCHEMBL9967018 | 0.88 | ESR1 (0.66) | PSMB1PSMB5PSMB2ESR1ESR2 | |
| SCHEMBL9966819 | 0.88 | ESR1 (0.66) | PSMB1PSMB5PSMB2ESR1ESR2 | |
| SCHEMBL9966824 | 0.87 | ESR1 (0.64) | ESR1ESR2 | |
| SCHEMBL9942715 | 0.86 | ESR1 (0.57) | OPRK1GCGRLTA4HPSMB1PSMB5 | |
| SCHEMBL9940337 | 0.86 | ESR1 (0.57) | OPRK1GCGRLTA4HPSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |