Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LTA4H | P09960 | 11/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | GCGR | P47871 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9942183 | 0.91 | GCGR (0.55) | LTA4HOPRK1GCGR | |
| SCHEMBL9940284 | 0.90 | OPRK1 (0.55) | KDM4ELTA4HOPRK1HRH3GCGR | |
| SCHEMBL9942716 | 0.90 | LTA4H (0.55) | LTA4HOPRK1HRH3GCGR | |
| SCHEMBL9942788 | 0.90 | OPRK1 (0.55) | KDM4ELTA4HOPRK1HRH3GCGR | |
| SCHEMBL9967026 | 0.89 | ESR1 (0.54) | KDM4ELTA4HALDH1A1LMNA | |
| SCHEMBL9936164 | 0.88 | LTA4H (0.54) | KDM4ELTA4HOPRK1ALDH1A1GCGR | |
| SCHEMBL9967004 | 0.88 | LTA4H (0.50) | KDM4ELTA4HOPRK1ALDH1A1LMNA | |
| SCHEMBL9940186 | 0.87 | HRH3 (0.51) | KDM4ELTA4HOPRK1ALDH1A1LMNA | |
| SCHEMBL9966786 | 0.86 | HRH3 (0.53) | KDM4ELTA4HOPRK1ALDH1A1LMNA | |
| SCHEMBL9966994 | 0.85 | KDM4E (0.48) | KDM4ELTA4HOPRK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |