Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
| ▸ | WDR5 | P61964 | 2/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404243 | 0.82 | TSHR (0.40) | LMNATSHRHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL418249 | 0.80 | LMNA (0.38) | LMNATSHRHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL419382 | 0.77 | ALDH1A1 (0.40) | LMNATSHRHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL3025240 | 0.76 | LMNA (0.42) | LMNATSHRHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL410941 | 0.74 | LMNA (0.38) | LMNATSHRHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL3034626 | 0.74 | TP53 (0.36) | LMNATSHRHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL2120025 | 0.72 | TSHR (0.33) | LMNATSHRHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL416125 | 0.72 | NR1I2 (0.34) | LMNATSHRHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL406454 | 0.71 | TSHR (0.41) | LMNATSHRHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL417562 | 0.71 | BACE1 (0.33) | LMNATSHRHPGDSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741806-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-06-03 | — | — | US | disclosed |
| US-20120190545-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-26 | — | — | US | disclosed |
| EP-2454224-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011006543-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190545-A1 | NOVEL HERBICIDES | DDT, CYP1B1, CYP1A1 | LMNA 4671/4885TSHR 1434/4885HPGD 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.