Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | GLS | O94925 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9935989 | 0.91 | GAA (0.59) | GAAHTTALDH1A1APOBEC3GGLS | |
| SCHEMBL9936025 | 0.87 | HTT (0.64) | GAAHTTALDH1A1APOBEC3GGLS | |
| SCHEMBL9936501 | 0.85 | HTT (0.58) | GAAHTTALDH1A1APOBEC3GGLS | |
| SCHEMBL9936633 | 0.84 | NAAA (0.59) | GAAHTTALDH1A1APOBEC3GGLS | |
| SCHEMBL9937447 | 0.84 | ALDH1A1 (0.56) | GAAHTTALDH1A1APOBEC3GGLS | |
| SCHEMBL9936178 | 0.84 | NAAA (0.59) | GAAHTTALDH1A1APOBEC3GGLS | |
| SCHEMBL9935825 | 0.83 | GAA (0.57) | GAAHTTALDH1A1APOBEC3GGLS | |
| SCHEMBL9937235 | 0.83 | GAA (0.52) | GAAHTTALDH1A1APOBEC3GGLS | |
| SCHEMBL9936998 | 0.81 | HPGD (0.61) | GAAHTTALDH1A1APOBEC3GGLS | |
| SCHEMBL12062497 | 0.81 | GAA (0.58) | GAAHTTALDH1A1APOBEC3GGLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651897-B1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | OREAL (FR) | 2020-04-01 | — | — | EP | claimed |
| EP-2651897-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'Oréal (FR) | 2013-10-23 | — | — | EP | claimed |
| WO-2012080075-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2012-06-21 | — | — | WO | claimed |
| US-20240293301-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2024-09-05 | — | — | US | disclosed |
| US-20210401709-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'ORÉAL (FR) | 2021-12-30 | — | — | US | disclosed |
| US-11052028-B2 | Process for depigmenting keratin materials using thiopyridinone compounds | L'OREAL (FR) | 2021-07-06 | — | — | US | disclosed |
| EP-2651897-B1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | OREAL (FR) | 2020-04-01 | — | — | EP | disclosed |
| US-20160045420-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2016-02-18 | — | — | US | disclosed |
| US-20160045420-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2016-02-18 | — | — | US | disclosed |
| US-9138392-B2 | Process for depigmenting keratin materials using thiopyridinone compounds | L'OREAL (FR) | 2015-09-22 | — | — | US | disclosed |
| US-9138392-B2 | Process for depigmenting keratin materials using thiopyridinone compounds | L'OREAL (FR) | 2015-09-22 | — | — | US | disclosed |
| WO-2012080075-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160045420-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | CBR3, RTN3, HRH4 | GAA 4768/4885HTT 1773/4885ALDH1A1 1647/4885 |
| US-20240293301-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | CBR3, RTN3, HRH4 | GAA 4771/4885HTT 1842/4885ALDH1A1 1679/4885 |
| US-20210401709-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | CBR3, HRH4, RTN3 | GAA 4751/4885HTT 1473/4885ALDH1A1 1705/4885 |
| US-11052028-B2 | Process for depigmenting keratin materials using thiopyridinone compounds | KRT18, PKN1, PTMA | GAA 2542/4885HTT 1114/4885ALDH1A1 1269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.