Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GLS | O94925 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936178 | 1.00 | NAAA (0.59) | NAAAHTTTSHRHPGDGAA | |
| SCHEMBL9936501 | 0.99 | HTT (0.58) | NAAAHTTTSHRHPGDGAA | |
| SCHEMBL9936025 | 0.94 | HTT (0.64) | NAAAHTTTSHRHPGDGAA | |
| SCHEMBL9935825 | 0.88 | GAA (0.57) | NAAAHTTTSHRHPGDGAA | |
| SCHEMBL9936307 | 0.84 | GAA (0.56) | HTTTSHRGAAALOX5ALDH1A1 | |
| SCHEMBL9937447 | 0.83 | ALDH1A1 (0.56) | HTTTSHRHPGDGAAALDH1A1 | |
| SCHEMBL9936998 | 0.83 | HPGD (0.61) | HTTTSHRHPGDGAAALDH1A1 | |
| SCHEMBL9936614 | 0.82 | GAA (0.56) | HTTTSHRGAAALDH1A1GLS | |
| SCHEMBL9935989 | 0.81 | GAA (0.59) | HTTTSHRGAAALDH1A1GLS | |
| SCHEMBL29038565 | 0.81 | HDAC3 (0.67) | NAAAHTTTSHRLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12521333-B2 | Composition comprising compound of thiopyridinone type and polyglyceryl-based emulsifiers | L'OREAL (FR) | 2026-01-13 | — | — | US | claimed |
| US-20250381116-A1 | SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | OREAL (FR) | 2025-12-18 | — | — | US | claimed |
| US-20250381115-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | OREAL (FR) | 2025-12-18 | — | — | US | claimed |
| US-20250375367-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | OREAL (FR) | 2025-12-11 | — | — | US | claimed |
| US-20250367096-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | OREAL (FR) | 2025-12-04 | — | — | US | claimed |
| US-20250205131-A1 | COSMETIC COMPOSITION COMPRISING THIOPYRIDINONE COMPOUNDS, REDUCING AGENT AND ARGININE | L'OREAL (FR) | 2025-06-26 | — | — | US | claimed |
| US-12226506-B2 | Cosmetic composition comprising natural emulsifiers and thiopyridinone compounds | L'OREAL (FR) | 2025-02-18 | — | — | US | claimed |
| US-20230404879-A1 | ENHANCING PHOTOSTABILITY OF THIOPYRIDINONE COMPOUND WITHOUT THE USE OF UV FILTERS | L'OREAL (FR) | 2023-12-21 | — | — | US | claimed |
| US-20230404882-A1 | COMPOSITION COMPRISING COMPOUND OF THIOPYRIDINONE TYPE AND POLYGLYCERYL-BASED EMULSIFIERS | L'OREAL (FR) | 2023-12-21 | — | — | US | claimed |
| US-20230404884-A1 | COSMETIC COMPOSITION COMPRISING HYDROPHILIC ANTIOXIDANTS AND THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2023-12-21 | — | — | US | claimed |
| US-20230404883-A1 | COSMETIC COMPOSITION COMPRISING NATURAL EMULSIFIERS AND THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2023-12-21 | — | — | US | claimed |
| EP-2651897-B1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | OREAL (FR) | 2020-04-01 | — | — | EP | claimed |
| EP-2651897-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'Oréal (FR) | 2013-10-23 | — | — | EP | claimed |
| WO-2012080075-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2012-06-21 | — | — | WO | claimed |
| US-12521333-B2 | Composition comprising compound of thiopyridinone type and polyglyceryl-based emulsifiers | L'OREAL (FR) | 2026-01-13 | — | — | US | disclosed |
| US-20250381116-A1 | SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | OREAL (FR) | 2025-12-18 | — | — | US | disclosed |
| US-20250381115-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | OREAL (FR) | 2025-12-18 | — | — | US | disclosed |
| US-9138392-B2 | Process for depigmenting keratin materials using thiopyridinone compounds | L'OREAL (FR) | 2015-09-22 | — | — | US | disclosed |
| US-9138392-B2 | Process for depigmenting keratin materials using thiopyridinone compounds | L'OREAL (FR) | 2015-09-22 | — | — | US | disclosed |
| WO-2012080075-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230404882-A1 | COMPOSITION COMPRISING COMPOUND OF THIOPYRIDINONE TYPE AND POLYGLYCERYL-BASED EMULSIFIERS | PPARG, PHOSPHO1, SQLE | NAAA 936/4885HTT 1061/4885TSHR 927/4885 |
| US-20230404884-A1 | COSMETIC COMPOSITION COMPRISING HYDROPHILIC ANTIOXIDANTS AND THIOPYRIDINONE COMPOUNDS | TPO, LPO, OGG1 | NAAA 3887/4885HTT 459/4885TSHR 1152/4885 |
| US-20250375367-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | TPMT, CRY1, TDP1 | NAAA 3881/4885HTT 42/4885TSHR 3430/4885 |
| US-20230404883-A1 | COSMETIC COMPOSITION COMPRISING NATURAL EMULSIFIERS AND THIOPYRIDINONE COMPOUNDS | PPARG, PHOSPHO1, POLQ | NAAA 1183/4885HTT 1025/4885TSHR 802/4885 |
| US-20250367096-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | TPMT, DHPS, MTAP | NAAA 2071/4885HTT 261/4885TSHR 2947/4885 |
| US-20250381115-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | TPMT, TPR, TYMP | NAAA 2403/4885HTT 280/4885TSHR 2271/4885 |
| US-12226506-B2 | Cosmetic composition comprising natural emulsifiers and thiopyridinone compounds | PPARG, PHOSPHO1, POLQ | NAAA 1183/4885HTT 1025/4885TSHR 802/4885 |
| US-20250205131-A1 | COSMETIC COMPOSITION COMPRISING THIOPYRIDINONE COMPOUNDS, REDUCING AGENT AND ARGININE | PRMT1, ARG1, PRMT5 | NAAA 2464/4885HTT 2106/4885TSHR 796/4885 |
| US-20250381116-A1 | SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | TBCB, CCNB3, CYP24A1 | NAAA 3748/4885HTT 3044/4885TSHR 2123/4885 |
| US-20230404879-A1 | ENHANCING PHOTOSTABILITY OF THIOPYRIDINONE COMPOUND WITHOUT THE USE OF UV FILTERS | TYR, TST, TSN | NAAA 1623/4885HTT 2662/4885TSHR 1178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.