Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.42 |
| ▸ | BCHE | P06276 | 6/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936584 | 1.00 | PTGS2 (0.42) | PTGS2BCHEACHEBLMPTGS1 | |
| SCHEMBL6951557 | 0.79 | ACHE (0.49) | PTGS2BCHEACHEBLMLMNA | |
| SCHEMBL6947233 | 0.74 | BCHE (0.44) | PTGS2BCHEACHELMNAPPARG | |
| SCHEMBL28780363 | 0.73 | LOXL2 (0.42) | LMNAHTR2ATSHRSMN1; SMN2MAPT | |
| SCHEMBL21303546 | 0.72 | KDM4E (0.61) | PTGS2BLMPTGS1LMNACYP2C9 | |
| SCHEMBL6948422 | 0.71 | BCHE (0.42) | PTGS2BCHEACHEPTGS1LMNA | |
| SCHEMBL6946512 | 0.71 | PTPRB (0.50) | PTGS2BCHEACHE | |
| SCHEMBL14180221 | 0.70 | ESR1 (0.45) | PTGS2BCHEACHEESR1HTR2A | |
| SCHEMBL6948598 | 0.69 | ACHE (0.44) | PTGS2BCHEACHEESR1EPHX1 | |
| SCHEMBL6948589 | 0.69 | LDHA (0.54) | PTGS2BCHEACHEBLMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651454-A1 | IMAGING AGENTS | Chroma Therapeutics Ltd. (GB) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080705-A1 | IMAGING AGENTS | CHROMA THERAPEUTICS LTD (GB) | 2012-06-21 | — | — | WO | disclosed |