Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.33 |
| ▸ | ITGAV | P06756 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL564213 | 0.74 | POLB (0.35) | LMNAALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL9936710 | 0.74 | — | — | |
| SCHEMBL16213092 | 0.70 | ALDH1A1 (0.62) | LMNAALDH1A1MIFNPC1RAB9A | |
| SCHEMBL16213506 | 0.69 | ALDH1A1 (0.32) | LMNAALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL18936052 | 0.69 | LMNA (0.48) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL9936193 | 0.67 | MIF (0.47) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL19194383 | 0.67 | ITGB3 (0.43) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL16213560 | 0.66 | NPC1 (0.34) | LMNAALDH1A1NPC1RAB9AATM | |
| SCHEMBL7682704 | 0.65 | SCN8A (0.36) | TDP1 | |
| SCHEMBL1979983 | 0.64 | TSHR (0.47) | LMNAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651219-A2 | FUNGICIDAL AZOCYCLIC AMIDES | E.I. Du Pont De Nemours And Company (US) | 2013-10-23 | — | — | EP | disclosed |
| US-20130261154-A1 | FUNGICIDAL AZOCYCLIC AMIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| WO-2012082580-A2 | FUNGICIDAL AZOCYCLIC AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261154-A1 | FUNGICIDAL AZOCYCLIC AMIDES | CYP51A1, Q6ZSR9, NOX1 | HDAC3 691/4885HDAC1 233/4885HDAC2 610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.