SCHEMBL9936874

SCHEMBL9936874

CCOC(C)COC(=O)C(F)F

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
TSHR P16473 2/20 0.32
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALOX15 P16050 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9936843 0.88 LMNA (0.33) LMNATSHRALDH1A1HSD17B10TDP1
SCHEMBL17150351 0.83 LMNA (0.36) LMNATSHRALDH1A1SMN1; SMN2HSD17B10
SCHEMBL9936545 0.81
SCHEMBL9936666 0.81 LMNA (0.35) LMNATSHRALDH1A1HSD17B10TDP1
SCHEMBL1469447 0.80 ALDH1A1 (0.48) LMNATSHRALDH1A1SMN1; SMN2HSD17B10
SCHEMBL27888652 0.80 TSHR (0.48) LMNATSHRALDH1A1SMN1; SMN2HSD17B10
SCHEMBL27625723 0.79 LMNA (0.33) LMNATSHRALDH1A1SMN1; SMN2HSD17B10
SCHEMBL9936953 0.79 PRKCA (0.34) LMNAMGAMGAASIMGAM2
SCHEMBL14905777 0.78 LMNA (0.36) LMNATSHRALDH1A1SMN1; SMN2HSD17B10
SCHEMBL2777851 0.78 ALDH1A1 (0.50) LMNATSHRALDH1A1SMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9472813-B2 Battery electrolyte solution containing certain ester-based solvents, and batteries containing such an electrolyte solution DOW GLOBAL TECHNOLOGIES LLC (US) 2016-10-18 US disclosed
EP-2652832-A1 BATTERY ELECTROLYTE SOLUTION CONTAINING CERTAIN ESTER-BASED SOLVENTS, AND BATTERIES CONTAINING SUCH AN ELECTROLYTE SOLUTION Dow Global Technologies LLC (US) 2013-10-23 EP disclosed
US-20130260229-A1 BATTERY ELECTROLYTE SOLUTION CONTAINING CERTAIN ESTER-BASED SOLVENTS, AND BATTERIES CONTAINING SUCH AN ELECTROLYTE SOLUTION DOW GLOBAL TECHNOLOGIES LLC (US) 2013-10-03 US disclosed
WO-2012082760-A1 BATTERY ELECTROLYTE SOLUTION CONTAINING CERTAIN ESTER-BASED SOLVENTS, AND BATTERIES CONTAINING SUCH AN ELECTROLYTE SOLUTION DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-21 WO disclosed